Percutaneous CT Fluoroscopy-Guided Core Needle Biopsy of Mediastinal Masses: Technical Outcome and Complications of 155 Procedures during a 10-Year Period
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Population
2.2. Peri-Interventional Imaging and Image Guidance
2.3. Procedure
2.4. Assessment of Technical Outcome and Complications
2.5. Patient Radiation Dose
2.6. Statistical Analysis
3. Results
3.1. Patient Characteristics
3.2. Intervention Characteristics
3.3. Technical Outcome and Complications
3.4. Post-Procedural Morbidity and Mortality
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Variable | Numbers (Percentage) | Mean Value ± SD (Range) |
---|---|---|
Age (years) | 54.7 ± 18.2 (20–89) | |
Sex | ||
Female | 63 (42.6) | |
Male | 85 (57.4) | |
Lesion size (cm) | 6.0 ± 3.3 (0.6–18.1) | |
Mediastinal localization | ||
Anterior | 114 (73.5) | |
Middle | 17 (11) | |
Posterior | 24 (15.5) |
Variable | Numbers (Percentage) | Mean Value ± SD (Range) |
---|---|---|
Access path | ||
Parasternal | 82 (52.9) | |
Paravertebral | 36 (23.2) | |
In the thoracic anterior midline | 17 (11) | |
Intercostal lateral | 20 (12.9) | |
Needle diameter (G) | ||
16 | 33 (21.3) | |
18 | 86 (55.5) | |
Not specified | 36 (23.2) | |
Number of samples | ||
1 | 41 (26.5) | |
2 | 51 (32.9) | |
More than 2 * | 21 (13.5) | |
3 | 22 (14.2) | |
4 | 3 (1.9) | |
5 | 1 (0.6) | |
Not specified | 16 (10.4) | |
Total effective radiation dose (Total DLP, mGy*cm) | 575.7 ± 488.8 (183–3811) |
Histopathology | Number | Percentage |
---|---|---|
Definite histopathologic diagnosis | 136/152 | 89.5 |
Malignant lesions | 115 | 75.7 |
Non-Hodgkin lymphoma | 38 | 25 |
Bronchial carcinoma/metastasis | 22 | 14.4 |
Hodgkin lymphoma | 13 | 8.6 |
Sarcoma/metastasis | 9 | 5.9 |
Malignant Thymoma | 5 | 3.2 |
Extramedullary manifestation of AML/ALL/chloroma | 5 | 3.2 |
Neuroendocrine tumor/metastasis | 4 | 2.6 |
Breast cancer/metastasis | 4 | 2.6 |
Carcinoma of unknown primary (CUP)/metastasis | 4 | 2.6 |
Renal cell carcinoma/metastasis | 3 | 2.0 |
Tonsil cancer/metastasis | 1 | 0.7 |
Choriocarcinoma/metastasis | 1 | 0.7 |
Oropharyngeal carcinoma/metastasis | 1 | 0.7 |
Pancreatic carcinoma/metastasis | 1 | 0.7 |
Stomach cancer/metastasis | 1 | 0.7 |
Colon cancer/metastasis | 1 | 0.7 |
Seminoma/metastasis | 1 | 0.7 |
Non-seminomatous tumor/metastasis | 1 | 0.7 |
Benign lesions | 35 | 23 |
Benign Thymoma | 11 | 7.2 |
Hematoma | 7 | 4.5 |
Pericardial cyst/effusion | 4 | 2.6 |
Thymus | 4 | 2.6 |
Mediastinal inflammatory pseudotumor | 2 | 1.3 |
Lymphadenitis | 2 | 1.3 |
Lipoma | 1 | 0.7 |
Struma | 1 | 0.7 |
Sclerosing mediastinitis | 1 | 0.7 |
Scar tissue | 1 | 0.7 |
Schwannoma | 1 | 0.7 |
Miscellaneous | 2 | 1.3 |
Teratoma | 2 | 1.3 |
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Burgard, C.; Stahl, R.; de Figueiredo, G.N.; Dinkel, J.; Liebig, T.; Cioni, D.; Neri, E.; Trumm, C.G. Percutaneous CT Fluoroscopy-Guided Core Needle Biopsy of Mediastinal Masses: Technical Outcome and Complications of 155 Procedures during a 10-Year Period. Diagnostics 2021, 11, 781. https://doi.org/10.3390/diagnostics11050781
Burgard C, Stahl R, de Figueiredo GN, Dinkel J, Liebig T, Cioni D, Neri E, Trumm CG. Percutaneous CT Fluoroscopy-Guided Core Needle Biopsy of Mediastinal Masses: Technical Outcome and Complications of 155 Procedures during a 10-Year Period. Diagnostics. 2021; 11(5):781. https://doi.org/10.3390/diagnostics11050781
Chicago/Turabian StyleBurgard, Caroline, Robert Stahl, Giovanna Negrao de Figueiredo, Julien Dinkel, Thomas Liebig, Dania Cioni, Emanuele Neri, and Christoph G. Trumm. 2021. "Percutaneous CT Fluoroscopy-Guided Core Needle Biopsy of Mediastinal Masses: Technical Outcome and Complications of 155 Procedures during a 10-Year Period" Diagnostics 11, no. 5: 781. https://doi.org/10.3390/diagnostics11050781