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Diagnostics
Volume 11
Issue 4
10.3390/diagnostics11040670
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Review
Peer-Review Record

Infantile Brain Tumors: A Review of Literature and Future Perspectives

Diagnostics 2021, 11(4), 670; https://doi.org/10.3390/diagnostics11040670
by Valeria Simone 1,*, Daniela Rizzo 1, Alessandro Cocciolo 1, Anna Maria Caroleo 2, Andrea Carai 3, Angela Mastronuzzi 2 and Assunta Tornesello 1,*
Reviewer 1: Anonymous
Reviewer 2: Anonymous
Diagnostics 2021, 11(4), 670; https://doi.org/10.3390/diagnostics11040670
Submission received: 15 March 2021 / Revised: 1 April 2021 / Accepted: 5 April 2021 / Published: 8 April 2021
(This article belongs to the Special Issue Advances in Pediatric Neuro-Oncology)

Round 1

Reviewer 1 Report

It should indicate the publication Infantile/Congenital High-Grade Gliomas: Molecular Features and Therapeutic Perspectives Giulia Ceglie 1,*et al of the same group in the discussion of the topic

Author Response

Please see the attachment

Author Response File: Author Response.doc

Reviewer 2 Report

Simone et al. present interesting review entitled”Infantile brain tumors: a review of literature and future perspectives”. This review highlights the recent advances in the diagnosis and treatment of brain tumors in infants, with a particular focus on the molecular landscape and future clinical applications.It seems to be an important voice in clinical discussion concerning pediatric malignancies.

Major 

figure 1 

Please expand description concerning presented signaling pathways


Add epigenetic aspect of each group of tumors(miRNas interplay)if present.

cite:

Mazurek, M.; Grochowski, C.; Litak, J.; Osuchowska, I.; Maciejewski, R.; Kamieniak, P. Recent Trends of microRNA Significance in Pediatric Population Glioblastoma and Current Knowledge of Micro RNA Function in Glioblastoma Multiforme. Int. J. Mol. Sci.2020, 21, 3046. https://doi.org/10.3390/ijms21093046

And another study

https://doi.org/10.3171/2020.2.PEDS19715

Last 5 years references ratio does not exceed 50% (oscylates around 30%)Please update

 

 

Author Response

Please see the attachment

Author Response File: Author Response.doc

Round 2

Reviewer 2 Report

Accept in current form.

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