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Open AccessCase Report

Anaplastic Thyroid Carcinoma Histologically Mimicking a Plasmacytoma

1
Department of Pathology and Laboratory Medicine, UC Irvine School of Medicine, Irvine, CA 92617, USA
2
Department of Otolaryngology-Head and Neck Surgery, University of California, Irvine, CA 92697, USA
*
Author to whom correspondence should be addressed.
Diagnostics 2020, 10(1), 29; https://doi.org/10.3390/diagnostics10010029
Received: 16 November 2019 / Revised: 30 December 2019 / Accepted: 3 January 2020 / Published: 8 January 2020
(This article belongs to the Special Issue Imaging-Histopathology Correlation)
Anaplastic (undifferentiated) thyroid carcinoma (ATC) is a rare malignancy which may arise from transformation of a pre-existing differentiated carcinoma. We report the unique case where a lesion of thyroid origin presented with the histological features of mature plasma cells. Immunohistochemistry confirmed the lesion to be an anaplastic thyroid carcinoma arising from papillary thyroid carcinoma. A tumor mimicking a malignancy of a different cellular origin can lead clinicians to incorrect treatment approaches. Careful correlation with clinical details and knowledge of these unique presentations is important for reaching the correct diagnosis. View Full-Text
Keywords: anaplastic thyroid carcinoma; plasmacytoma; mimic anaplastic thyroid carcinoma; plasmacytoma; mimic
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MDPI and ACS Style

Mo, J.H.; Tan, D.; Zhao, X.S.; Tjoa, T.; Wang, B.Y. Anaplastic Thyroid Carcinoma Histologically Mimicking a Plasmacytoma. Diagnostics 2020, 10, 29.

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