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Opinion

Is Research on “Synthetic Cells” Moving to the Next Level?

Department of Biological and Environmental Sciences and Technologies (DiSTeBA), University of Salento; Ecotekne—S.P. Lecce-Monteroni, I-73100 Lecce, Italy
Received: 4 December 2018 / Revised: 20 December 2018 / Accepted: 21 December 2018 / Published: 26 December 2018
(This article belongs to the Special Issue Approaches toward Artificial Cell Construction and Applications)
“Synthetic cells” research focuses on the construction of cell-like models by using solute-filled artificial microcompartments with a biomimetic structure. In recent years this bottom-up synthetic biology area has considerably progressed, and the field is currently experiencing a rapid expansion. Here we summarize some technical and theoretical aspects of synthetic cells based on gene expression and other enzymatic reactions inside liposomes, and comment on the most recent trends. Such a tour will be an occasion for asking whether times are ripe for a sort of qualitative jump toward novel SC prototypes: is research on “synthetic cells” moving to a next level? View Full-Text
Keywords: artificial cells; autopoiesis; cell-free protein synthesis; complexity; liposomes; microfluidics; numerical modeling; origins of life; protocells; synthetic biology; synthetic cells artificial cells; autopoiesis; cell-free protein synthesis; complexity; liposomes; microfluidics; numerical modeling; origins of life; protocells; synthetic biology; synthetic cells
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MDPI and ACS Style

Stano, P. Is Research on “Synthetic Cells” Moving to the Next Level? Life 2019, 9, 3. https://doi.org/10.3390/life9010003

AMA Style

Stano P. Is Research on “Synthetic Cells” Moving to the Next Level? Life. 2019; 9(1):3. https://doi.org/10.3390/life9010003

Chicago/Turabian Style

Stano, Pasquale. 2019. "Is Research on “Synthetic Cells” Moving to the Next Level?" Life 9, no. 1: 3. https://doi.org/10.3390/life9010003

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