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Case Report

Combination of Manuka Honey and Chitosan-Based Biomaterial for the Treatment of Dehisced Wound: Case Report

by
Zuzana Šufliarska
1,2,
Katarína Vdoviaková
1,
Lenka Krešáková
1,
Ján Danko
1,
Pavol Rusnák
1,
Ľubomír Medvecký
1,3,
Mária Giretová
3,
Jozef Bíreš
4,
Filip Humeník
1,5 and
Jana Pobehová
6,7,*
1
Department of Morphological Sciences, University of Veterinary Medicine and Pharmacy in Košice, 041 81 Košice, Slovakia
2
PET Point Veterinary Clinic, 984 01 Lučenec, Slovakia
3
Division of Functional and Hybrid Systems, Institute of Materials Research of SAS, 040 01 Košice, Slovakia
4
Clinic of Ruminants, University of Veterinary Medicine and Pharmacy in Košice, 041 81 Košice, Slovakia
5
Clinic of Burns and Reconstructive Medicine, AGEL Teaching Hospital, 040 15 Košice-Šaca, Slovakia
6
Faculty of Medicine, Pavol Jozef Šafárik Univeristy in Košice, SNP 1, 040 11 Košice, Slovakia
7
East Slovak Institute of Cardiovascular Diseases, Ondavská 8, 040 01 Košice, Slovakia
*
Author to whom correspondence should be addressed.
Life 2026, 16(8), 1279; https://doi.org/10.3390/life16081279
Submission received: 26 June 2026 / Revised: 27 July 2026 / Accepted: 31 July 2026 / Published: 1 August 2026
(This article belongs to the Special Issue Stem Cell Biology, Tissue Formation, Cell Plasticity and Regenerative Medicine)
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Abstract

Background: Surgical wound dehiscence (SWD) is defined as a complete or partial separation of the surgical incision site after surgery and represents a serious complication in soft tissue surgery. Case presentation: We present a clinical case of wound dehiscence in a 7-month-old dachshund. The primary cause was an attack by another dog, leading to the development of a deep bite wound in the back area perforating the anus and numerous minor injuries in the same area. After initial treatment and apparently good general health, numerous necrotic foci were observed during wound cleaning on the 3rd day after treatment. The wound was subsequently revised and an experimentally developed biomaterial based on chitosan in combination with manuka honey was applied. The use of this combination resulted in an accelerated healing process and almost complete closure of the wound already on the 12th day after application. Conclusions: This case demonstrates and simultaneously points to the promising possibilities of using chitosan-based biomaterials and honey as natural products for the successful treatment of wounds and management of postoperative complications.
Keywords: wound healing; dehiscence; manuka honey; chitosan; biomaterial wound healing; dehiscence; manuka honey; chitosan; biomaterial
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MDPI and ACS Style

Šufliarska, Z.; Vdoviaková, K.; Krešáková, L.; Danko, J.; Rusnák, P.; Medvecký, Ľ.; Giretová, M.; Bíreš, J.; Humeník, F.; Pobehová, J. Combination of Manuka Honey and Chitosan-Based Biomaterial for the Treatment of Dehisced Wound: Case Report. Life 2026, 16, 1279. https://doi.org/10.3390/life16081279

AMA Style

Šufliarska Z, Vdoviaková K, Krešáková L, Danko J, Rusnák P, Medvecký Ľ, Giretová M, Bíreš J, Humeník F, Pobehová J. Combination of Manuka Honey and Chitosan-Based Biomaterial for the Treatment of Dehisced Wound: Case Report. Life. 2026; 16(8):1279. https://doi.org/10.3390/life16081279

Chicago/Turabian Style

Šufliarska, Zuzana, Katarína Vdoviaková, Lenka Krešáková, Ján Danko, Pavol Rusnák, Ľubomír Medvecký, Mária Giretová, Jozef Bíreš, Filip Humeník, and Jana Pobehová. 2026. "Combination of Manuka Honey and Chitosan-Based Biomaterial for the Treatment of Dehisced Wound: Case Report" Life 16, no. 8: 1279. https://doi.org/10.3390/life16081279

APA Style

Šufliarska, Z., Vdoviaková, K., Krešáková, L., Danko, J., Rusnák, P., Medvecký, Ľ., Giretová, M., Bíreš, J., Humeník, F., & Pobehová, J. (2026). Combination of Manuka Honey and Chitosan-Based Biomaterial for the Treatment of Dehisced Wound: Case Report. Life, 16(8), 1279. https://doi.org/10.3390/life16081279

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