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Volume 15
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10.3390/life15121847
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Article

Chemical Characteristics and Biological Potential of Prunus laurocerasus Fruits

by
Mina Todorova
1,*,
Nadezhda Petkova
2,
Ivan Ivanov
2,
Yulian Tumbarski
3,
Velichka Yanakieva
3,
Ivelina Vasileva
2,
Yoana Barakova
1,
Emiliya Cherneva
4 and
Stoyanka Nikolova
1,*
1
Department of Organic Chemistry, Faculty of Chemistry, University of Plovdiv, 4000 Plovdiv, Bulgaria
2
Department of Organic Chemistry and Inorganic Chemistry, University of Food Technologies, 26 Maritsa Blvd., 4002 Plovdiv, Bulgaria
3
Department of Microbiology, Technological Faculty, University of Food Technologies, 4002 Plovdiv, Bulgaria
4
Department of Chemistry, Faculty of Pharmacy, Medical University of Sofia, 2 Dunav Str., 1000 Sofia, Bulgaria
*
Authors to whom correspondence should be addressed.
Life 2025, 15(12), 1847; https://doi.org/10.3390/life15121847 (registering DOI)
Submission received: 28 October 2025 / Revised: 27 November 2025 / Accepted: 28 November 2025 / Published: 30 November 2025
(This article belongs to the Special Issue Therapeutic Approaches of Natural Products in Health and Disease)
Versions Notes

Abstract

Fruits of the Laurocerasus officinalis Roem., known as cherry laurel, are found in the Black Sea region. This study examines the phytochemical characterization, antioxidant properties, and antimicrobial potential of cherry laurel’s fruits, variety Novita, cultivated in Southern Bulgaria. The study is significant since it examines the phytochemical profile of this variety’s fruits for the first time. The carbohydrate composition of the fruit was identified. The total polyphenols and flavonoids of five fruit extracts (96% ethanol, 70% ethanol, 50% ethanol, 80% methanol, and water) were determined. The antioxidant potential of these five extracts was evaluated by three methods: DPPH, ABTS, and FRAP. We found that the 96% ethanol extract had the highest content of polyphenols and flavonoids and the highest antioxidant activity values by all three methods. A correlation was established between the content of polyphenols, flavonoids, and antioxidant activity based on the calculated correlation coefficient. The antimicrobial potential of methanolic and aqueous extracts of the fruit of the laurel cherry was evaluated against twenty microorganisms. It was found that the methanolic extracts exhibited moderate to high sensitivity against both Gram-positive and Gram-negative strains, yeast Saccharomyces cerevisiae, and five fungi, while water extracts had moderately sensitive activity against Micrococcus luteus only. Based on the results, we can conclude that the fruits demonstrate good antioxidant and antimicrobial potential.
Keywords: antimicrobial activity; antioxidant activity; carbohydrate composition; chemical characteristics; laurel cherry; total phenolics content; total flavonoids content antimicrobial activity; antioxidant activity; carbohydrate composition; chemical characteristics; laurel cherry; total phenolics content; total flavonoids content

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MDPI and ACS Style

Todorova, M.; Petkova, N.; Ivanov, I.; Tumbarski, Y.; Yanakieva, V.; Vasileva, I.; Barakova, Y.; Cherneva, E.; Nikolova, S. Chemical Characteristics and Biological Potential of Prunus laurocerasus Fruits. Life 2025, 15, 1847. https://doi.org/10.3390/life15121847

AMA Style

Todorova M, Petkova N, Ivanov I, Tumbarski Y, Yanakieva V, Vasileva I, Barakova Y, Cherneva E, Nikolova S. Chemical Characteristics and Biological Potential of Prunus laurocerasus Fruits. Life. 2025; 15(12):1847. https://doi.org/10.3390/life15121847

Chicago/Turabian Style

Todorova, Mina, Nadezhda Petkova, Ivan Ivanov, Yulian Tumbarski, Velichka Yanakieva, Ivelina Vasileva, Yoana Barakova, Emiliya Cherneva, and Stoyanka Nikolova. 2025. "Chemical Characteristics and Biological Potential of Prunus laurocerasus Fruits" Life 15, no. 12: 1847. https://doi.org/10.3390/life15121847

APA Style

Todorova, M., Petkova, N., Ivanov, I., Tumbarski, Y., Yanakieva, V., Vasileva, I., Barakova, Y., Cherneva, E., & Nikolova, S. (2025). Chemical Characteristics and Biological Potential of Prunus laurocerasus Fruits. Life, 15(12), 1847. https://doi.org/10.3390/life15121847

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