Subretinal Transplant of Human Amniotic Membrane in Advanced Age-Related Macular Degeneration
Abstract
:1. Introduction
2. Materials and Methods
2.1. Patients
2.2. Study Exams
2.3. Statistical Analysis
2.4. Surgical Technique
3. Discussion
4. Results
4.1. MNV-Group
4.2. Atrophic Group
4.3. OCT-A Results
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Patient ID/Age (YO)/Sex | Eye | Lens Status | Preoperative BCVA—Snellen (LogMAR) | 1-Month BCVA—Snellen (LogMAR) | 3-Month BCVA—Snellen (LogMAR) | 6-Month BCVA—Snellen (LogMAR) | 12-Month BCVA—Snellen (LogMAR) |
---|---|---|---|---|---|---|---|
1/70/F | Right | phakic | 20/2000 (2) | 20/400 (1.3) | 20/100 (0.7) | 20/2000 (2) | 20/400 (1.3) |
2/68/M | Right | pseudophakic | 20/2000 (2) | 20/2000 (2) | 20/400 (1.3) | 20/400 (1.3) | 20/200 (1) |
3/80/F | Right | pseudophakic | 20/2000 (2) | 20/2000 (2) | 20/400 (1.3) | 20/100 (0.7) | 20/100 (0.7) |
4/80/M | Right | phakic | 20/2000 (2) | 20/2000 (2) | 20/2000 (2) | 20/2000 (2) | 20/2000 (2) |
5/72/F | Left | pseudophakic | 20/2000 (2) | 20/2000 (2) | 20/2000 (2) | 20/400 (1.3) | 20/400 (1.3) |
6/68/M | Right | phakic | 20/2000 (2) | 20/400 (1.3) | 20/400 (1.3) | 20/400 (1.3) | 20/400 (1.3) |
7/85/F | Left | pseudophakic | 20/2000 (2) | 20/2000 (2) | 20/800 (1.6) | 20/800 (1.6) | 20/400 (1.3) |
8/86/F | Left | pseudophakic | 20/2000 (2) | 20/2000 (2) | 20/400 (1.3) | 20/400 (1.3) | 20/400 (1.3) |
9/79/M | Right | pseudophakic | 20/800 (1.6) | 20/200 (1) | 20/200 (1) | 20/125 (0.8) | 20/100 (0.7) |
10/85/M | Right | pseudophakic | 20/800 (1.6) | 20/200 (1) | 20/200 (1) | 20/200 (1) | 20/200 (1) |
11/87/M | Right | pseudophakic | 20/2000 (2) | 20/2000 (2) | 20/2000 (2) | 20/400 (1.3) | 20/200 (1) |
12/83/F | Left | phakic | 20/2000 (2) | 20/2000 (2) | 20/2000 (2) | 20/2000 (2) | 20/2000 (2) |
13/75/F | Left | phakic | 20/200 (1) | 20/200 (1) | 20/160 (0.9) | 20/100 (0.7) | 20/80 (0.6) |
14/84/M | Right | pseudophakic | 20/2000 (2) | 20/400 (1.3) | 20/400 (1.3) | 20/200 (1) | 20/200 (1) |
15/73/M | Left | phakic | 20/2000 (2) | 20/160 (0.9) | 20/160 (0.9) | 20/200 (1) | 20/125 (0.8) |
15/73/M | Right | phakic | 20/20,000 (3) | 20/400 (1.3) | 20/400 (1.3) | 20/400 (1.3) | 20/400 (1.3) |
16/80/F | Right | pseudophakic | 20/2000 (2) | 20/2000 (2) | 20/2000 (2) | 20/2000 (2) | 20/2000 (2) |
17/88/F | Left | pseudophakic | 20/2000 (2) | 20/2000 (2) | 20/400 (1.3) | 20/400 (1.3) | 20/400 (1.3) |
18/80/M | Right | pseudophakic | 20/800 (1.6) | 20/2000 (2) | 20/400 (1.3) | 20/400 (1.3) | 20/200 (1) |
19/78/M | Right | pseudophakic | 20/800 (1.6) | 20/200 (1) | 20/200 (1) | 20/200 (1) | 20/200 (1) |
20/78/F | Right | phakic | 20/20,000 (3) | 20/20,000 (3) | 20/20,000 (3) | 20/20,000 (3) | 20/20,000 (3) |
21/75/F | Left | pseudophakic | 20/400 (1.3) | 20/200 (1) | 20/200 (1) | 20/100 (0.7) | 20/80 (0.6) |
21/75/F | Right | pseudophakic | 20/200 (1) | 20/200 (1) | 20/125 (0.8) | 20/100 (0.7) | 20/63 (0.5) |
Patient ID/Age (YO)/Sex | Eye | Lens Status | Preoperative BCVA—Snellen (LogMAR) | 1-Month BCVA—Snellen (LogMAR) | 3-Month BCVA—Snellen (LogMAR) | 6-Month BCVA—Snellen (LogMAR) | 12-Month BCVA—Snellen (LogMAR) |
---|---|---|---|---|---|---|---|
1/80/M | Right | phakic | 20/2000 (2) | 20/2000 (2) | 20/2000 (2) | 20/2000 (2) | 20/2000 (2) |
2/85/F | Left | pseudophakic | 20/2000 (2) | 20/2000 (2) | 20/800 (1.6) | 20/400 (1.3) | 20/400 (1.3) |
3/86/F | Left | pseudophakic | 20/2000 (2) | 20/2000 (2) | 20/400 (1.3) | 20/400 (1.3) | 20/400 (1.3) |
4/79/M | Right | pseudophakic | 20/800 (1.6) | 20/200 (1) | 20/200 (1) | 20/125 (0.8) | 20/100 (0.7) |
5/85/M | Right | pseudophakic | 20/800 (1.6) | 20/200 (1) | 20/200 (1) | 20/200 (1) | 20/200 (1) |
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Caporossi, T.; Scampoli, A.; Baldascino, A.; Gambini, G.; Pacini, B.; Governatori, L.; Bacherini, D.; Carlà, M.M.; Crincoli, E.; Rizzo, C.; et al. Subretinal Transplant of Human Amniotic Membrane in Advanced Age-Related Macular Degeneration. Life 2022, 12, 1998. https://doi.org/10.3390/life12121998
Caporossi T, Scampoli A, Baldascino A, Gambini G, Pacini B, Governatori L, Bacherini D, Carlà MM, Crincoli E, Rizzo C, et al. Subretinal Transplant of Human Amniotic Membrane in Advanced Age-Related Macular Degeneration. Life. 2022; 12(12):1998. https://doi.org/10.3390/life12121998
Chicago/Turabian StyleCaporossi, Tomaso, Alessandra Scampoli, Antonio Baldascino, Gloria Gambini, Bianca Pacini, Lorenzo Governatori, Daniela Bacherini, Matteo Mario Carlà, Emanuele Crincoli, Clara Rizzo, and et al. 2022. "Subretinal Transplant of Human Amniotic Membrane in Advanced Age-Related Macular Degeneration" Life 12, no. 12: 1998. https://doi.org/10.3390/life12121998