Perioperative Prevention of Venous Thromboembolism in Abdominal Surgery Patients Based on the Caprini or the Padua Risk Score—A Single Centre Prospective Observational Study
Abstract
:1. Introduction
2. Patients and Methods
3. Statistical Analysis
4. Results
5. Discussion
Limitations
6. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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All (n = 223) | Caprini Score Used (n = 122) | Padua Score Used (n = 101) | p (Caprini vs. Padua) | ||
---|---|---|---|---|---|
Gender | male, n (%) | 118 (53) | 59 (48) | 59 (58) | 0.134 |
female, n (%) | 105 (47) | 63 (52) | 43 (42) | ||
Age | years, mean (SD) | 59.8 (14.7) | 60.9 (14.9) | 58.3 (14.1) | 0.190 |
Diagnosis | non-malignant, n (%) | 122 (55) | 59 (48) | 42 (42) | 0.311 |
malignant, n (%) | 101 (45) | 63 (52) | 59 (58) | ||
Major surgery | n (%) | 198 (89) | 111 (92) | 87 (86) | 0.252 |
Smokers | n (%) | 45 (20) | 21 (20) | 24 (24) | 0.225 |
Confirmed COVID-19 during observation | n (%) | 15 (6.7) | 5 (4.1) | 10 (9.9) | 0.085 |
All (n = 223) | Caprini Score Used (n = 122) | Padua Score Used (n = 101) | p (Caprini vs. Padua Used) | ||
---|---|---|---|---|---|
Caprini score | Median | 5 | 4.5 | 5 | 0.156 |
25th percentile | 4 | 4 | 4 | ||
75th percentile | 7 | 7 | 7 | ||
Padua score | Median | 1 | 1 | 1 | 0.936 |
25th percentile | 0 | 0 | 0 | ||
75th percentile | 4 | 3 | 4 | ||
Adverse outcome | Composite | 15 | 6 | 9 | 0.236 |
Death | 10 | 3 | 7 | 0.108 | |
VTE | 5 | 3 | 2 | 0.810 |
Composite Adverse Outcome | Death | Symptomatic Venous Thromboembolism | ||||
---|---|---|---|---|---|---|
With/All (No.) | OR (95% CI), p | With/All (No.) | OR (95% CI), p | With/All (No.) | OR (95% CI), p | |
High vs. Non-high Caprini Score | 15/151 vs. 0/72 | ∞ (∞), - | 10/151 vs. 0/72 | ∞ (∞), - | 5/151 vs. 0/72 | ∞ (∞), - |
High vs. Non-high Padua Score | 10/67 vs. 5/156 | 5.30 (1.74–16.17), p = 0.0017 | 9/67 vs. 1/156 | 24.05 (2.98–194.05), p = 0.0014 | 1/67 vs. 4/156 | 0.58 (0.06–5.25), p = 0.3122 |
Malignant vs. Benign Diagnosis | 10/101 vs. 5/122 | 2.57 (0.85–7.79), p = 0.0473 | 9/101 vs. 1/122 | 11.84 (1.47–95.1), p = 0.0100 | 1/101 vs. 4/122 | 0.30 (0.003–2.68), p = 0.1392 |
Male vs. Female Gender | 9/118 vs. 6/105 | 1.36 (0.47–3.96), p = 0.2852 | 5/118 vs. 5/105 | 0.88 (0.25–3.15), p = 0.4251 | 4/118 vs. 1/105 | 3.65 (0.40–33.18), p = 0.1251 |
Age ≥65 y vs. <65 y | 12/96 vs. 3/127 | 5.90 (1.62–21.56), p = 0.0036 | 7/96 vs. 3/127 | 3.25 (0.82–12.92), p = 0.0469 | 5/96 vs. 0/127 | ∞ (∞), - |
Smoker vs. Non-smoker | 6/45 vs. 9/178 | 2.89 (0.97–8.59), p = 0.0282 | 4/45 vs. 6/178 | 2.80 (0.75–10.37), p = 0.0619 | 2/45 vs. 3/178 | 2.71 (0.44–16.75), p = 0.1412 |
COVID-19 vs. No COVID-19 | 2/15 vs. 13/208 | 2.31 (0.47–11.33), p = 0.1514 | 1/15 vs. 9/208 | 1.58 (0.19–13.37), p = 0.3374 | 1/15 vs. 4/208 | 3.64 (0.38–34.81), p = 0.1308 |
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Klen, J.; Horvat, G.; Blinc, A. Perioperative Prevention of Venous Thromboembolism in Abdominal Surgery Patients Based on the Caprini or the Padua Risk Score—A Single Centre Prospective Observational Study. Life 2022, 12, 1843. https://doi.org/10.3390/life12111843
Klen J, Horvat G, Blinc A. Perioperative Prevention of Venous Thromboembolism in Abdominal Surgery Patients Based on the Caprini or the Padua Risk Score—A Single Centre Prospective Observational Study. Life. 2022; 12(11):1843. https://doi.org/10.3390/life12111843
Chicago/Turabian StyleKlen, Jasna, Gašper Horvat, and Aleš Blinc. 2022. "Perioperative Prevention of Venous Thromboembolism in Abdominal Surgery Patients Based on the Caprini or the Padua Risk Score—A Single Centre Prospective Observational Study" Life 12, no. 11: 1843. https://doi.org/10.3390/life12111843