Next Article in Journal
Statins in COVID-19 Therapy
Next Article in Special Issue
Timely and Blood-Based Multiplex Molecular Profiling of Acute Stroke
Previous Article in Journal
The Metabolic Bone Disease X-linked Hypophosphatemia: Case Presentation, Pathophysiology and Pharmacology
Previous Article in Special Issue
Insulin-Like Growth Factor-II and Ischemic Stroke—A Prospective Observational Study
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Life
Volume 11
Issue 6
10.3390/life11060564
life-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Article

Surgery for Coagulopathy-Related Intracerebral Hemorrhage: Craniotomy vs. Minimally Invasive Neurosurgery

by
Yen-Bo Liu
1,†,
Lu-Ting Kuo
1,†,
Chih-Hao Chen
2,
Woon-Man Kung
3,
Hsin-Hsi Tsai
2,4,
Sheng-Chieh Chou
5,
Shih-Hung Yang
1,
Kuo-Chuan Wang
1,
Dar-Ming Lai
1 and
Abel Po-Hao Huang
1,*
1
Department of Surgery, Division of Neurosurgery, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei 10617, Taiwan
2
Department of Neurology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei 10617, Taiwan
3
Department of Exercise and Health Promotion, College of Kinesiology and Health, Chinese Culture University, Taipei 11114, Taiwan
4
Department of Neurology, National Taiwan University Hospital Bei-Hu Branch, Taipei 10617, Taiwan
5
Department of Internal Medicine, Division of Hematology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei 10617, Taiwan
*
Author to whom correspondence should be addressed.
†
These authors contributed equally to this work.
Life 2021, 11(6), 564; https://doi.org/10.3390/life11060564
Submission received: 11 May 2021 / Revised: 3 June 2021 / Accepted: 9 June 2021 / Published: 15 June 2021
(This article belongs to the Special Issue Innovative Stroke Diagnostic and Treatment Strategies)
Browse Figure
Versions Notes

Abstract

Coagulopathy-related intracerebral hemorrhage (ICH) is life-threatening. Recent studies have shown promising results with minimally invasive neurosurgery (MIN) in the reduction of mortality and improvement of functional outcomes, but no published data have recorded the safety and efficacy of MIN for coagulopathy-related ICH. Seventy-five coagulopathy-related ICH patients were retrospectively reviewed to compare the surgical outcomes between craniotomy (n = 52) and MIN (n = 23). Postoperative rebleeding rates, morbidity rates, and mortality at 1 month were analyzed. Postoperative Glasgow Outcome Scale Extended (GOSE) and modified Rankin Scale (mRS) scores at 1 year were assessed for functional outcomes. Morbidity, mortality, and rebleeding rates were all lower in the MIN group than the craniotomy group (8.70% vs. 30.77%, 8.70% vs. 19.23%, and 4.35% vs. 23.08%, respectively). The 1-year GOSE score was significantly higher in the MIN group than the craniotomy group (3.96 ± 1.55 vs. 3.10 ± 1.59, p = 0.027). Multivariable logistic regression analysis also revealed that MIN contributed to improved GOSE (estimate: 0.99650, p = 0.0148) and mRS scores (estimate: −0.72849, p = 0.0427) at 1 year. MIN, with low complication rates and improved long-term functional outcome, is feasible and favorable for coagulopathy-related ICH. This promising result should be validated in a large-scale prospective study.
Keywords: intracerebral hemorrhage; coagulopathy; minimally invasive neurosurgery; comparison of surgical outcomes intracerebral hemorrhage; coagulopathy; minimally invasive neurosurgery; comparison of surgical outcomes

Share and Cite

MDPI and ACS Style

Liu, Y.-B.; Kuo, L.-T.; Chen, C.-H.; Kung, W.-M.; Tsai, H.-H.; Chou, S.-C.; Yang, S.-H.; Wang, K.-C.; Lai, D.-M.; Huang, A.P.-H. Surgery for Coagulopathy-Related Intracerebral Hemorrhage: Craniotomy vs. Minimally Invasive Neurosurgery. Life 2021, 11, 564. https://doi.org/10.3390/life11060564

AMA Style

Liu Y-B, Kuo L-T, Chen C-H, Kung W-M, Tsai H-H, Chou S-C, Yang S-H, Wang K-C, Lai D-M, Huang AP-H. Surgery for Coagulopathy-Related Intracerebral Hemorrhage: Craniotomy vs. Minimally Invasive Neurosurgery. Life. 2021; 11(6):564. https://doi.org/10.3390/life11060564

Chicago/Turabian Style

Liu, Yen-Bo, Lu-Ting Kuo, Chih-Hao Chen, Woon-Man Kung, Hsin-Hsi Tsai, Sheng-Chieh Chou, Shih-Hung Yang, Kuo-Chuan Wang, Dar-Ming Lai, and Abel Po-Hao Huang. 2021. "Surgery for Coagulopathy-Related Intracerebral Hemorrhage: Craniotomy vs. Minimally Invasive Neurosurgery" Life 11, no. 6: 564. https://doi.org/10.3390/life11060564

APA Style

Liu, Y.-B., Kuo, L.-T., Chen, C.-H., Kung, W.-M., Tsai, H.-H., Chou, S.-C., Yang, S.-H., Wang, K.-C., Lai, D.-M., & Huang, A. P.-H. (2021). Surgery for Coagulopathy-Related Intracerebral Hemorrhage: Craniotomy vs. Minimally Invasive Neurosurgery. Life, 11(6), 564. https://doi.org/10.3390/life11060564

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop