The Growing Complexity of UHRF1-Mediated Maintenance DNA Methylation
Abstract
1. Introduction
2. DNMT1 is an Autoinhibited DNA Methyltransferase
3. UHRF1 is Required for Proper Loading of DNMT1 onto Chromatin
4. Allosteric Regulation of UHRF1 E3 Ubiquitin Ligase Activity
5. UHRF1-Dependent Histone H3 Ubiquitination Stimulates DNMT1 Enzymatic Activity
6. DNMT1 Recruitment and Stimulation by UHRF1 N-Terminal UBL Domain
7. Epigenetic Crosstalk between DNA Methylation and Histone Modifications in Maintenance DNA Methylation
8. A Working Model for DNMT1/UHRF1 Complex in Maintenance DNA Methylation
9. Future Perspective
Funding
Acknowledgments
Conflicts of Interest
References
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Xie, S.; Qian, C. The Growing Complexity of UHRF1-Mediated Maintenance DNA Methylation. Genes 2018, 9, 600. https://doi.org/10.3390/genes9120600
Xie S, Qian C. The Growing Complexity of UHRF1-Mediated Maintenance DNA Methylation. Genes. 2018; 9(12):600. https://doi.org/10.3390/genes9120600
Chicago/Turabian StyleXie, Si, and Chengmin Qian. 2018. "The Growing Complexity of UHRF1-Mediated Maintenance DNA Methylation" Genes 9, no. 12: 600. https://doi.org/10.3390/genes9120600
APA StyleXie, S., & Qian, C. (2018). The Growing Complexity of UHRF1-Mediated Maintenance DNA Methylation. Genes, 9(12), 600. https://doi.org/10.3390/genes9120600