Systemic EBV+ T-Cell Lymphoma of Childhood with Hemophagocytic Lymphohistiocytosis in a Patient with a Highly Complex Karyotype
Abstract
:1. Introduction
2. Detailed Case Description
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Parameter | Finding/Value | Reference Range |
---|---|---|
Temperature | 39.4 °C | 36.1–37.2 °C |
Hemoglobin | 8.0 g/dL | 12.0–16.0 g/dL |
Platelet count | 53 × 103 µL | 150–400 × 103 µL |
Absolute neutrophil count | 0.72 × 103 µL | 1.7–7.00 × 103 µL |
Triglycerides | 608 mg/dL | <150 mg/dL |
Fibrinogen | 166 mg/dL | 173–454 mg/dL |
Ferritin | >13,000 ng/mL | 11–204 ng/mL |
Splenomegaly | 22.7 cm | <12 cm |
Soluble CD25 | 66,395.7 pg/mL | 175.3–858.2 pg/mL |
CXCL9 | 89,046 pg/mL | <647 pg/mL |
EBV Quant PCR | 218,658 IU/mL | Not detectable |
Hemophagocytosis in marrow | Present | Absent |
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Maher, P.; Guzman, E.; Chaffin, J.; Kashif, R.; Burnside, R.D. Systemic EBV+ T-Cell Lymphoma of Childhood with Hemophagocytic Lymphohistiocytosis in a Patient with a Highly Complex Karyotype. Genes 2025, 16, 382. https://doi.org/10.3390/genes16040382
Maher P, Guzman E, Chaffin J, Kashif R, Burnside RD. Systemic EBV+ T-Cell Lymphoma of Childhood with Hemophagocytic Lymphohistiocytosis in a Patient with a Highly Complex Karyotype. Genes. 2025; 16(4):382. https://doi.org/10.3390/genes16040382
Chicago/Turabian StyleMaher, Patrick, Emilia Guzman, Joanna Chaffin, Reema Kashif, and Rachel D. Burnside. 2025. "Systemic EBV+ T-Cell Lymphoma of Childhood with Hemophagocytic Lymphohistiocytosis in a Patient with a Highly Complex Karyotype" Genes 16, no. 4: 382. https://doi.org/10.3390/genes16040382
APA StyleMaher, P., Guzman, E., Chaffin, J., Kashif, R., & Burnside, R. D. (2025). Systemic EBV+ T-Cell Lymphoma of Childhood with Hemophagocytic Lymphohistiocytosis in a Patient with a Highly Complex Karyotype. Genes, 16(4), 382. https://doi.org/10.3390/genes16040382