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Open AccessReview

The Influence of Diet and Obesity on Gene Expression in SLE

Department of Medicine, University of California Los Angeles, 1000 Veteran Ave. 32-59, Los Angeles, CA 90095-1670, USA
Genes 2019, 10(5), 405; https://doi.org/10.3390/genes10050405
Received: 26 March 2019 / Revised: 17 May 2019 / Accepted: 22 May 2019 / Published: 27 May 2019
(This article belongs to the Special Issue Gene-Diet Interactions in Obesity)
This review provides an overview of the known effects of diet, obesity, and the intake of different nutrients on systemic lupus erythematosus (SLE). It summarizes and discusses the studies in rodents that identified how different diets can regulate gene expression in the disease, together with a description of the effects of diet on lupus patients’ inflammatory state and disease severity. The identification of selected dietary candidates that can modulate SLE onset and progression is analyzed in relation to possible targeted approaches that could ultimately ameliorate the management and prognosis of this disease. View Full-Text
Keywords: diet; obesity; systemic lupus erythematosus diet; obesity; systemic lupus erythematosus
MDPI and ACS Style

La Cava, A. The Influence of Diet and Obesity on Gene Expression in SLE. Genes 2019, 10, 405.

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