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NOP53 as A Candidate Modifier Locus for Familial Non-Medullary Thyroid Cancer
Open AccessReview

Influencers on Thyroid Cancer Onset: Molecular Genetic Basis

1
Department of Maternofetal Medicine, Genetics and Reproduction, Institute of Biomedicine of Seville (IBIS), University Hospital Virgen del Rocío/CSIC/University of Seville, 41013 Seville, Spain
2
Centre for Biomedical Network Research on Rare Diseases (CIBERER), 41013 Seville, Spain
*
Author to whom correspondence should be addressed.
Genes 2019, 10(11), 913; https://doi.org/10.3390/genes10110913
Received: 3 September 2019 / Revised: 25 October 2019 / Accepted: 6 November 2019 / Published: 8 November 2019
(This article belongs to the Special Issue Thyroid Cancer: Genetics and Targeted Therapies)
Thyroid cancer, a cancerous tumor or growth located within the thyroid gland, is the most common endocrine cancer. It is one of the few cancers whereby incidence rates have increased in recent years. It occurs in all age groups, from children through to seniors. Most studies are focused on dissecting its genetic basis, since our current knowledge of the genetic background of the different forms of thyroid cancer is far from complete, which poses a challenge for diagnosis and prognosis of the disease. In this review, we describe prevailing advances and update our understanding of the molecular genetics of thyroid cancer, focusing on the main genes related with the pathology, including the different noncoding RNAs associated with the disease.
Keywords: thyroid cancer; genetics; epigenetics; mutation thyroid cancer; genetics; epigenetics; mutation
MDPI and ACS Style

Luzón-Toro, B.; Fernández, R.M.; Villalba-Benito, L.; Torroglosa, A.; Antiñolo, G.; Borrego, S. Influencers on Thyroid Cancer Onset: Molecular Genetic Basis. Genes 2019, 10, 913.

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