Implications of Selective Autophagy Dysfunction for ALS Pathology
Abstract
1. Introduction
1.1. Amyotrophic Lateral Sclerosis (ALS)
1.2. Autophagy Pathways
2. Autophagy and ALS
3. Selective Autophagy in ALS
3.1. P62
3.2. Optineurin (OPTN)
3.3. Ubiquilin-2 (UBQLN2)
3.4. Valosin-Containing Protein (VCP)
3.5. TANK Binding Kinase 1 (TBK1)
4. Convergence of Different Pathways in ALS on Autophagy
5. Therapeutic Approaches Based on Autophagy
6. Conclusions
Author Contributions
Acknowledgments
Conflicts of Interest
References
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Vicencio, E.; Beltrán, S.; Labrador, L.; Manque, P.; Nassif, M.; Woehlbier, U. Implications of Selective Autophagy Dysfunction for ALS Pathology. Cells 2020, 9, 381. https://doi.org/10.3390/cells9020381
Vicencio E, Beltrán S, Labrador L, Manque P, Nassif M, Woehlbier U. Implications of Selective Autophagy Dysfunction for ALS Pathology. Cells. 2020; 9(2):381. https://doi.org/10.3390/cells9020381
Chicago/Turabian StyleVicencio, Emiliano, Sebastián Beltrán, Luis Labrador, Patricio Manque, Melissa Nassif, and Ute Woehlbier. 2020. "Implications of Selective Autophagy Dysfunction for ALS Pathology" Cells 9, no. 2: 381. https://doi.org/10.3390/cells9020381
APA StyleVicencio, E., Beltrán, S., Labrador, L., Manque, P., Nassif, M., & Woehlbier, U. (2020). Implications of Selective Autophagy Dysfunction for ALS Pathology. Cells, 9(2), 381. https://doi.org/10.3390/cells9020381