Next Article in Journal
Cardiac Rhythm and Molecular Docking Studies of Ion Channel Ligands with Cardiotoxicity in Zebrafish
Next Article in Special Issue
The Role of Phosphatases in Nuclear Envelope Disassembly and Reassembly and Their Relevance to Pathologies
Previous Article in Journal
Autophagy in Synucleinopathy: The Overwhelmed and Defective Machinery
Previous Article in Special Issue
Recent Progress on the Localization of the Spindle Assembly Checkpoint Machinery to Kinetochores
Open AccessReview

Recent Research Advances in Mitosis during Mammalian Gametogenesis

1
Beijing Key Laboratory for Animal Genetic Improvement, National Engineering Laboratory for Animal Breeding, Key Laboratory of Animal Genetics and Breeding of the Ministry of Agriculture, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China
2
CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China
3
State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China
*
Authors to whom correspondence should be addressed.
These authors contributed equally to this work.
Cells 2019, 8(6), 567; https://doi.org/10.3390/cells8060567
Received: 22 April 2019 / Revised: 2 June 2019 / Accepted: 6 June 2019 / Published: 10 June 2019
(This article belongs to the Special Issue Molecular Regulation of Mitosis and Its Role in Disease)
Mitosis is a highly sophisticated and well-regulated process during the development and differentiation of mammalian gametogenesis. The regulation of mitosis plays an essential role in keeping the formulation in oogenesis and gametogenesis. In the past few years, substantial research progress has been made by showing that cyclins/cyclin-dependent kinase (CDK) have roles in the regulation of meiosis. In addition, more functional signaling molecules have been discovered in mitosis. Growing evidence has also indicated that miRNAs influence cell cycling. In this review, we focus on specific genes, cyclins/Cdk, signaling pathways/molecules, and miRNAs to discuss the latest achievements in understanding their roles in mitosis during gametogenesis. Further elucidation of mitosis during gametogenesis may facilitate delineating all processes of mammalian reproduction and the development of disease treatments. View Full-Text
Keywords: mitosis; mammalian gametes; cyclins/Cdk mitosis; mammalian gametes; cyclins/Cdk
Show Figures

Figure 1

MDPI and ACS Style

Wang, J.-H.; Li, Y.; Deng, S.-L.; Liu, Y.-X.; Lian, Z.-X.; Yu, K. Recent Research Advances in Mitosis during Mammalian Gametogenesis. Cells 2019, 8, 567.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop