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Minichromosomes: Vectors for Crop Improvement

Division of Biological Sciences, University of Missouri, 311 Tucker Hall, Columbia, MO 65211-7400, USA
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Academic Editor: Gareth Norton
Agronomy 2015, 5(3), 309-321;
Received: 15 May 2015 / Revised: 14 June 2015 / Accepted: 24 June 2015 / Published: 6 July 2015
(This article belongs to the Special Issue Accumulation and Distribution of Elements in Crop Plants)
PDF [368 KB, uploaded 6 July 2015]


Minichromosome technology has the potential to offer a number of possibilities for expanding current biofortification strategies. While conventional genome manipulations rely on random integration of one or a few genes, engineered minichromosomes would enable researchers to concatenate several gene aggregates into a single independent chromosome. These engineered minichromosomes can be rapidly transferred as a unit to other lines through the utilization of doubled haploid breeding. If used in conjunction with other biofortification methods, it may be possible to significantly increase the nutritional value of crops. View Full-Text
Keywords: minichromosomes; biofortification; B chromosomes; telomere truncation; BIBAC; genetic engineering; haploid induction minichromosomes; biofortification; B chromosomes; telomere truncation; BIBAC; genetic engineering; haploid induction

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Cody, J.P.; Swyers, N.C.; McCaw, M.E.; Graham, N.D.; Zhao, C.; Birchler, J.A. Minichromosomes: Vectors for Crop Improvement. Agronomy 2015, 5, 309-321.

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