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Polymers 2016, 8(4), 115;

Biodegradable Polymer Membranes Applied in Guided Bone/Tissue Regeneration: A Review

Department of Prosthodontics, Affiliated Stomatological Hospital of Nanchang University, Nanchang 330006, China
College of Chemistry, Nanchang University, Nanchang 330031, China
College of Science, Nanchang Institute of Technology, Nanchang 330029, China
Authors to whom correspondence should be addressed.
Academic Editor: Jianxun Ding
Received: 27 February 2016 / Revised: 20 March 2016 / Accepted: 24 March 2016 / Published: 29 March 2016
(This article belongs to the Special Issue Functional Polymers for Medical Applications)
PDF [1426 KB, uploaded 29 March 2016]


Polymer membranes have been widely used in guided tissue regeneration (GTR) and guided bone regeneration (GBR). In this review, various commercially available membranes are described. Much attention is paid to the recent development of biodegradable polymers applied in GTR and GBR, and the important issues of biodegradable polymeric membranes, including their classification, latest experimental research and clinical applications, as well as their main challenges are addressed. Herein, natural polymers, synthetic polymers and their blends are all introduced. Pure polymer membranes are biodegradable and biocompatible, but they lack special properties such as antibacterial properties, osteoconductivity, and thus polymer membranes loaded with functional materials such as antibacterial agents and growth factors show many more advantages and have also been introduced in this review. Despite there still being complaints about polymer membranes, such as their low mechanical properties, uncontrollable degradation speed and some other drawbacks, these problems will undoubtedly be conquered and biodegradable polymers will have more applications in GTR and GBR. View Full-Text
Keywords: biodegradable polymer; GTR; GBR; membrane; collagen; polylactide biodegradable polymer; GTR; GBR; membrane; collagen; polylactide

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Wang, J.; Wang, L.; Zhou, Z.; Lai, H.; Xu, P.; Liao, L.; Wei, J. Biodegradable Polymer Membranes Applied in Guided Bone/Tissue Regeneration: A Review. Polymers 2016, 8, 115.

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