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Open AccessReview

Start a Research on Biopolymer Polyhydroxyalkanoate (PHA): A Review

Residues and Resource Reclamation Centre, Nanyang Environment and Water Research Institute, Nanyang Technological University, 1 Cleantech Loop, 637141, Singapore
Division of Environmental and Water Resources, School of Civil and Environmental Engineering, Nanyang Technological University, 50 Nanyang Avenue, 639798, Singapore
Author to whom correspondence should be addressed.
Polymers 2014, 6(3), 706-754;
Received: 30 January 2014 / Revised: 21 February 2014 / Accepted: 27 February 2014 / Published: 12 March 2014
(This article belongs to the Special Issue Polymers from Biomass)
With the impending fossil fuel crisis, the search for and development of alternative chemical/material substitutes is pivotal in reducing mankind’s dependency on fossil resources. One of the potential substitute candidates is polyhydroxyalkanoate (PHA). PHA is a carbon-neutral and valuable polymer that could be produced from many renewable carbon sources by microorganisms, making it a sustainable and environmental-friendly material. At present, PHA is not cost competitive compared to fossil-derived products. Encouraging and intensifying research work on PHA is anticipated to enhance its economic viability in the future. The development of various biomolecular and chemical techniques for PHA analysis has led to the identification of many PHA-producing microbial strains, some of which are deposited in culture collections. Research work on PHA could be rapidly initiated with these ready-to-use techniques and microbial strains. This review aims to facilitate the start-up of PHA research by providing a summary of commercially available PHA-accumulating microbial cultures, PHA biosynthetic pathways, and methods for PHA detection, extraction and analysis. View Full-Text
Keywords: polyhydroxyalkanoate; PHA; biopolymer; bacteria; archaea; pathway; PHA detection; PHA extraction; PHA characterization polyhydroxyalkanoate; PHA; biopolymer; bacteria; archaea; pathway; PHA detection; PHA extraction; PHA characterization
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Tan, G.-Y.A.; Chen, C.-L.; Li, L.; Ge, L.; Wang, L.; Razaad, I.M.N.; Li, Y.; Zhao, L.; Mo, Y.; Wang, J.-Y. Start a Research on Biopolymer Polyhydroxyalkanoate (PHA): A Review. Polymers 2014, 6, 706-754.

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