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Review

CeO2 Nanoparticle-Containing Polymers for Biomedical Applications: A Review

1
Zabolotny Institute of Microbiology and Virology, National Academy of Sciences of Ukraine, 03680 Kyiv, Ukraine
2
Department of Textiles, Merchandising and Interiors, University of Georgia, Athens, GA, 30602, USA
3
Institute of Macromolecular Compounds, Russian Academy of Sciences, 199004 St. Petersburg, Russia
4
Kurnakov Institute of General and Inorganic Chemistry of the Russian Academy of Sciences, 119991 Moscow, Russia
5
Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, 142290 Moscow, Russia
*
Author to whom correspondence should be addressed.
Academic Editor: Iole Venditti
Polymers 2021, 13(6), 924; https://doi.org/10.3390/polym13060924
Received: 20 February 2021 / Revised: 11 March 2021 / Accepted: 14 March 2021 / Published: 17 March 2021
(This article belongs to the Special Issue Metal Nanoparticles–Polymers Hybrid Materials II)
The development of advanced composite biomaterials combining the versatility and biodegradability of polymers and the unique characteristics of metal oxide nanoparticles unveils new horizons in emerging biomedical applications, including tissue regeneration, drug delivery and gene therapy, theranostics and medical imaging. Nanocrystalline cerium(IV) oxide, or nanoceria, stands out from a crowd of other metal oxides as being a truly unique material, showing great potential in biomedicine due to its low systemic toxicity and numerous beneficial effects on living systems. The combination of nanoceria with new generations of biomedical polymers, such as PolyHEMA (poly(2-hydroxyethyl methacrylate)-based hydrogels, electrospun nanofibrous polycaprolactone or natural-based chitosan or cellulose, helps to expand the prospective area of applications by facilitating their bioavailability and averting potential negative effects. This review describes recent advances in biomedical polymeric material practices, highlights up-to-the-minute cerium oxide nanoparticle applications, as well as polymer-nanoceria composites, and aims to address the question: how can nanoceria enhance the biomedical potential of modern polymeric materials? View Full-Text
Keywords: biocomposites; hybrid materials; nanomaterials; therapy; COVID-19 biocomposites; hybrid materials; nanomaterials; therapy; COVID-19
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MDPI and ACS Style

Shcherbakov, A.B.; Reukov, V.V.; Yakimansky, A.V.; Krasnopeeva, E.L.; Ivanova, O.S.; Popov, A.L.; Ivanov, V.K. CeO2 Nanoparticle-Containing Polymers for Biomedical Applications: A Review. Polymers 2021, 13, 924. https://doi.org/10.3390/polym13060924

AMA Style

Shcherbakov AB, Reukov VV, Yakimansky AV, Krasnopeeva EL, Ivanova OS, Popov AL, Ivanov VK. CeO2 Nanoparticle-Containing Polymers for Biomedical Applications: A Review. Polymers. 2021; 13(6):924. https://doi.org/10.3390/polym13060924

Chicago/Turabian Style

Shcherbakov, Alexander B., Vladimir V. Reukov, Alexander V. Yakimansky, Elena L. Krasnopeeva, Olga S. Ivanova, Anton L. Popov, and Vladimir K. Ivanov 2021. "CeO2 Nanoparticle-Containing Polymers for Biomedical Applications: A Review" Polymers 13, no. 6: 924. https://doi.org/10.3390/polym13060924

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