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Open AccessReview

The Use of Poly(N-vinyl pyrrolidone) in the Delivery of Drugs: A Review

Department of Industrial Engineering, University of Salerno, Via Giovanni Paolo II, 132, 84084 Fisciano (SA), Italy
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Polymers 2020, 12(5), 1114; https://doi.org/10.3390/polym12051114
Received: 19 April 2020 / Revised: 6 May 2020 / Accepted: 9 May 2020 / Published: 13 May 2020
(This article belongs to the Special Issue Polymers and Drug Delivery Systems)
Polyvinylpyrrolidone (PVP) is a hydrophilic polymer widely employed as a carrier in the pharmaceutical, biomedical, and nutraceutical fields. Up to now, several PVP-based systems have been developed to deliver different active principles, of both natural and synthetic origin. Various formulations and morphologies have been proposed using PVP, including microparticles and nanoparticles, fibers, hydrogels, tablets, and films. Its versatility and peculiar properties make PVP one of the most suitable and promising polymers for the development of new pharmaceutical forms. This review highlights the role of PVP in drug delivery, focusing on the different morphologies proposed for different polymer/active compound formulations. It also provides detailed information on active principles and used technologies, optimized process parameters, advantages, disadvantages, and final applications. View Full-Text
Keywords: polyvinylpyrrolidone; drug delivery systems; microparticles; nanoparticles; fibers; hydrogels; tablets; films polyvinylpyrrolidone; drug delivery systems; microparticles; nanoparticles; fibers; hydrogels; tablets; films
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MDPI and ACS Style

Franco, P.; De Marco, I. The Use of Poly(N-vinyl pyrrolidone) in the Delivery of Drugs: A Review. Polymers 2020, 12, 1114.

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