Biopolymer Coatings for Biomedical Applications
Abstract
:1. Introduction
2. Polymer Coatings and Films
3. Biopolymer Coating Methods
4. Biopolymer Coatings on Metal Implants
5. Biopolymer Coatings for Surface Modification
5.1. Polyvinylidene Fluoride (PVDF)
5.2. Polymethyl Methacrylate (PMMA)
5.3. Polypropylene (PP)
5.4. Polydimethylsiloxane (PDMS)
5.5. Polyurethane (PU)
6. Other Biopolymer Coatings
7. Biopolymer Coatings on Nanoparticles
8. Conclusions and Future Prospects
Funding
Conflicts of Interest
References
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Coatings Material | Coating Method | Substrate/Nanoparticle | Applications Area | Refs. |
---|---|---|---|---|
poly(2-methyl-2-oxazoline) (PMOXA) | Electrochemical non brush bionic coating | 316L stainless steel | bioactivity, antifouling properties, prevent late stent thrombosis and in-stent restenosis | [15] |
Polytetrafluoroethylene | PEO coating | magnesium alloy MA8 | protective and antifriction properties | [16] |
hydroxyapatite- polytetrafluoroethylene | PEO coating | Mg–Mn–Ce alloys | corrosion resistance and impart bioactivity | [17] |
1. CaP coating 2. polylactic acid | immersion dip coating | magnesium | corrosion resistance and elongation of degradation time | [18] |
phosphate/collagen (CaP/Col) composite coatings | Chemical conversion and dip coating | Magnesium alloys | corrosion resistance and inducing bioactivity | [19] |
PVDF | Spin coating | Free standing ZnO grown film | wearable and wireless pressure sensor for heart rate monitoring | [31] |
R-GO/P(VDF-TrFE) | liquid phase blending Spin coating | Flexible and glass substrate | flexible, optically transparent, and highly responsive temperature sensor | [40] |
polyaniline-coated PVDF | Electrospinning in situ conversion | Aluminum foil | Human health monitoring | [45] |
PVDF-nanosilica | Electrospinning | Aluminum foil | Increased piezoelectric property for biomedical application | [46] |
PVDF/conducting polymer | Electrospinning | aluminum foil | Electrical conductivity and bioactivity | [47] |
P(VDF-TrFE) | Electrospinning | aluminum foil | implanted energy harvester, bioactivity | [48] |
PMMA | Alkali activation and surface-initiated atom transfer radical polymerization | Titanium | hybrid prosthesis, bioactivity | [52,53] |
methacrylate | modelling | Titanium | less susceptible biofilm formation coating, bioactivity | [54] |
PMMA/PDDA | spin coating or casting and drying | Si, glass, or polystyrene sheets | Antimicrobial coating | [55] |
PMMA/AgNPs-CS | immersion method | Soft rubber | Antimicrobial coating | [56] |
PDA | cold oxygen plasma | PP hernia mesh | drug absorption and longer release, antibacterial properties | [58] |
PVP:PEGDA | Cross-linking | PP | hydrophilicity and bioactivity | [61] |
Poly(StBP) | Spreading and curing with UV | PP | Bone tissue engineering | [62] |
cell-adhesive peptide | Dip coating | PDMS | functionalize biomedical devices with sensitive and complex components | [63] |
poly(acrylamide–acrylic acid) | Chemical bonding | PDMS | Ultralow friction coatings | [65] |
chlorhexidine (CHX)-loaded PDMS | oxygen plasma and heat treatment | 3D-printed dental polymer | induce surface wettability, microstructure, and antibacterial activity | [66] |
PDA and hyaluronic acid | drop casting | PDMS | Hemocompatible medical device and implant | [67] |
PDMS | low-energy electron beam irradiation | PDMS | long-lasting hydrophilic surface | [68] |
PTFE | Printing/Solution injection and curing | PDMS | To encapsulate anti-inflammatory drugs, super hydrophobicity | [69] |
PU | casting | Freestanding films | Biodegradable material for biomedical application | [70] |
PU/Ag | end-capped with functional groups | freestanding | developing medical device coatings and associated applications | [76] |
Isopropyl Myristate | casting | PU | bioactivity and low water permeability | [77] |
PU/graphene | electrospinning | Aluminum foil | electroconductivity, bioactivity and mechanical properties | [80] |
PLA/ZnO | Dip coating | Mg alloy (AZ31) | Reduced Mg degradation rate | [81] |
PLLA | Dip coating | PDMS stamp | Drug delivery application | [82] |
PCL | PEO and dip coating | Mg screw | Bone forming ability and osteogenesis | [83] |
PCL/FHA composite duplex coating | Dip coatings | Mg alloy | bioactivity and controlled Mg degradation | [84] |
PCL/PU/apatite | Electrospinning | Aluminum foil | controlled drug delivery | [86] |
Different polymer coatings | Polymer adsorption | Iron oxide nanorods | perfectly stabile colloidal nanoparticle for medical application | [97] |
PMSEA | RAFT polymerization | iron oxide nanoparticles | extended blood circulation time and reduced accumulation | [90] |
Chitosan | encapsulation | magnetic silica nanoparticles | pH/thermos-chemotherapy using an AMF drug delivery system | [99] |
Chitosan | adsorption | Mg0.5Co0.5Fe2O4 | Drug delivery | [100] |
Chitosan -PMAA | in situ polymerization | Fe3O4 MNPs | DOX delivery in breast cancer treatment | [101] |
PSS/PEI | LBL | AuNPs | Drug delivery to the layers of skin in melanoma treatment | [102] |
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Nathanael, A.J.; Oh, T.H. Biopolymer Coatings for Biomedical Applications. Polymers 2020, 12, 3061. https://doi.org/10.3390/polym12123061
Nathanael AJ, Oh TH. Biopolymer Coatings for Biomedical Applications. Polymers. 2020; 12(12):3061. https://doi.org/10.3390/polym12123061
Chicago/Turabian StyleNathanael, A. Joseph, and Tae Hwan Oh. 2020. "Biopolymer Coatings for Biomedical Applications" Polymers 12, no. 12: 3061. https://doi.org/10.3390/polym12123061