Next Article in Journal
Melamine–Glyoxal–Glutaraldehyde Wood Panel Adhesives without Formaldehyde
Next Article in Special Issue
Effect of Dendrigraft Generation on the Interaction between Anionic Polyelectrolytes and Dendrigraft Poly(l-Lysine)
Previous Article in Journal
Improving Kinetics of “Click-Crosslinking” for Self-Healing Nanocomposites by Graphene-Supported Cu-Nanoparticles
Previous Article in Special Issue
Preparation and Material Application of Amylose-Polymer Inclusion Complexes by Enzymatic Polymerization Approach
Open AccessArticle

Antibacterial Films Made of Ionic Complexes of Poly(γ-glutamic acid) and Ethyl Lauroyl Arginate

1
Departament d’Enginyeria Química, Universitat Politècnica de Catalunya, ETSEIB, Diagonal 647, 08028 Barcelona, Spain
2
Health and Environmental Microbiology Lab & UNESCO Chair on Sustainability, Universitat Politècnica de Catalunya, ESEIAAT, Edifici Gaia, Pg. Ernest Lluch/Rambla Sant Nebridi, 08222 Terrassa, Spain
*
Author to whom correspondence should be addressed.
Polymers 2018, 10(1), 21; https://doi.org/10.3390/polym10010021
Received: 23 November 2017 / Revised: 15 December 2017 / Accepted: 20 December 2017 / Published: 24 December 2017
(This article belongs to the Special Issue Host-Guest Polymer Complexes)
The biocide agent LAE (ethyl αN-lauroyl l-arginate chloride) was coupled with poly(γ-glutamic acid) (PGGA) to form stable ionic complexes with LAE:PGGA ratios of 1 and 0.5. The nanostructure adopted by these complexes and its response to thermal changes were examined in detail by Differential scanning calorimetry (DSC) and X-ray diffraction (XRD) using synchrotron radiation in real time. A layered biphasic structure with LAE filling the space between the polypeptidic sheets was adopted in these complexes. The complexes were stable up to above 250 °C, non-water soluble, and were able to form consistent transparent films. The release of LAE from the complexes upon incubation in aqueous buffer was examined and found to depend on both pH and complex composition. The antibacterial activity of films made of these complexes against Gram-positive (L. monocytogenes and S. aureus) and Gram-negative (E. coli and S. enterica) bacteria was preliminary evaluated and was found to be very high against the formers and only moderate against the later. The bactericide activity displayed by the LAE·PGGA complexes was directly related with the amount of LAE that was released from the film to the environment. View Full-Text
Keywords: ionic polyglutamic acid complexes; biocide polyglutamic acid; comb-like polyglutamic acid complexes; ethyl lauroyl arginate; antibacterial polymer complexes ionic polyglutamic acid complexes; biocide polyglutamic acid; comb-like polyglutamic acid complexes; ethyl lauroyl arginate; antibacterial polymer complexes
Show Figures

Graphical abstract

MDPI and ACS Style

Gamarra-Montes, A.; Missagia, B.; Morató, J.; Muñoz-Guerra, S. Antibacterial Films Made of Ionic Complexes of Poly(γ-glutamic acid) and Ethyl Lauroyl Arginate. Polymers 2018, 10, 21.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop