Next Article in Journal
Influence of the Titanium Content in the Ti-MCM-41 Catalyst on the Course of the α-Pinene Isomerization Process
Previous Article in Journal
Optical Properties, Electronic Structures, and Photocatalytic Performances of Bandgap-Tailored SrBi2Nb2−xVxO9 Compounds
Open AccessReview

Biomimetic Cu/Nitroxyl Catalyst Systems for Selective Alcohol Oxidation

Catalysis and Synthesis Research Group, Focus Area for Chemical Resource Beneficiation, North-West University, 11 Hoffman Street, Potchefstroom 2520, South Africa
*
Author to whom correspondence should be addressed.
Catalysts 2019, 9(5), 395; https://doi.org/10.3390/catal9050395
Received: 25 March 2019 / Revised: 16 April 2019 / Accepted: 18 April 2019 / Published: 26 April 2019
The oxidation of alcohols to the corresponding carbonyl products is an important organic transformation and the products are used in a variety of applications. The development of catalytic methods for selective alcohol oxidation have garnered significant attention in an attempt to find a more sustainable method without any limitations. Copper, in combination with 2,2,6,6-tetramethyl-1-piperidine N-oxyl (TEMPO) and supported by organic ligands, have emerged as the most effective catalysts for selective alcohol oxidation and these catalyst systems are frequently compared to galactose oxidase (GOase). The efficiency of GOase has led to extensive research to mimic the active sites of these enzymes, leading to a variety of Cu/TEMPO· catalyst systems being reported over the years. The mechanistic pathway by which Cu/TEMPO· catalyst systems operate has been investigated by several research groups, which led to partially contradicting mechanistic description. Due to the disadvantages and limitations of employing TEMPO· as co-catalyst, alternative nitroxyl radicals or in situ formed radicals, as co-catalysts, have been successfully evaluated in alcohol oxidation. Herein we discuss the development and mechanistic elucidation of Cu/TEMPO· catalyst systems as biomimetic alcohol oxidation catalysts. View Full-Text
Keywords: alcohol oxidation; copper catalysis; 2,2,6,6-tetramethyl-1-piperidine N-oxyl (TEMPO·), radical; galactose oxidase (GOase); mechanistic pathway alcohol oxidation; copper catalysis; 2,2,6,6-tetramethyl-1-piperidine N-oxyl (TEMPO·), radical; galactose oxidase (GOase); mechanistic pathway
Show Figures

Figure 1

MDPI and ACS Style

Marais, L.; Swarts, A.J. Biomimetic Cu/Nitroxyl Catalyst Systems for Selective Alcohol Oxidation. Catalysts 2019, 9, 395.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop