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Developmental Drift and the Role of Wnt Signaling in Aging

1
Yale-NUS College, Singapore 138527, Singapore
2
Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore
3
Department of Biological Sciences, National University of Singapore, Singapore 138615, Singapore
*
Author to whom correspondence should be addressed.
Academic Editors: Renee van Amerongen and Walter Birchmeier
Cancers 2016, 8(8), 73; https://doi.org/10.3390/cancers8080073
Received: 20 May 2016 / Revised: 12 July 2016 / Accepted: 25 July 2016 / Published: 2 August 2016
(This article belongs to the Special Issue Wnt Signaling in Cancer)
Population aging is a public health problem affecting the majority of the developed world. As populations age, the incidence of degenerative diseases increases exponentially, leading to large increases in public spending on healthcare. Here we summarize recent findings on the developmental drift theory of aging, and the links that have been established between aging and the Wnt signaling pathways. We focus on insights derived from model organisms connecting the evolutionary basis of aging and the link to developmental programming. View Full-Text
Keywords: wnt; aging; developmental drift wnt; aging; developmental drift
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MDPI and ACS Style

Gruber, J.; Yee, Z.; Tolwinski, N.S. Developmental Drift and the Role of Wnt Signaling in Aging. Cancers 2016, 8, 73. https://doi.org/10.3390/cancers8080073

AMA Style

Gruber J, Yee Z, Tolwinski NS. Developmental Drift and the Role of Wnt Signaling in Aging. Cancers. 2016; 8(8):73. https://doi.org/10.3390/cancers8080073

Chicago/Turabian Style

Gruber, Jan; Yee, Zhuangli; Tolwinski, Nicholas S. 2016. "Developmental Drift and the Role of Wnt Signaling in Aging" Cancers 8, no. 8: 73. https://doi.org/10.3390/cancers8080073

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Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

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