Next Article in Journal
Targeting the Sonic Hedgehog Signaling Pathway: Review of Smoothened and GLI Inhibitors
Next Article in Special Issue
Melanoma and the Unfolded Protein Response
Previous Article in Journal
Breast Cancer-Associated Fibroblasts: Where We Are and Where We Need to Go
Previous Article in Special Issue
Updates in Therapy for Advanced Melanoma
Article Menu

Export Article

Open AccessArticle

Conditional Melanoma Cancer Survival in the United States

Department of Health Science, Brigham Young University, Provo, UT 84602, USA
Author to whom correspondence should be addressed.
Academic Editor: Chyi-Chia Richard Lee
Cancers 2016, 8(2), 20;
Received: 25 November 2015 / Revised: 15 January 2016 / Accepted: 28 January 2016 / Published: 2 February 2016
(This article belongs to the Special Issue Current Topics in Cutaneous Melanoma)
PDF [1193 KB, uploaded 2 February 2016]


Beyond relative survival, which indicates the likelihood that patients will not die from causes associated with their cancer, conditional relative survival probabilities provide further useful prognostic information to cancer patients, tailored to the time already survived from diagnosis. This study presents conditional relative survival for melanoma patients in the United States, diagnosed during 2000–2008 and followed through 2012. Analyses are based on 62,803 male and 50,261 female cases in population-based cancer registries in the Surveillance, Epidemiology, and End Results Program of the National Cancer Institute. Five-year relative survival estimates are presented for melanoma patients who have already survived one, two, three, four, or five years after the initial diagnosis. Five- and ten-year relative survival decreases with age, stage at diagnosis, and is lower among males, Blacks, and Hispanics. Five-year conditional relative survival improves with each year already survived. The potential for improvement in five-year conditional relative survival is greatest for older age, males, Blacks, Hispanics, and in later staged cases. For local disease, five-year conditional relative survival was significantly lower in ages greater than 65 years and in Blacks. It was significantly higher in females, non-Hispanics, and married individuals. Age had a greater inverse relationship with five-year survival in later staged disease. A similar result occurred for females and married individuals. In contrast, non-Hispanics had better five-year survival if diagnosed with local or regional disease, but not distant disease. View Full-Text
Keywords: cancer; conditional survival; population-based; prognosis; relative survival; SEER cancer; conditional survival; population-based; prognosis; relative survival; SEER

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

Share & Cite This Article

MDPI and ACS Style

Merrill, R.M.; Bateman, S. Conditional Melanoma Cancer Survival in the United States. Cancers 2016, 8, 20.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Cancers EISSN 2072-6694 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top