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Review
Peer-Review Record

Integrating AI and ML in Myelodysplastic Syndrome Diagnosis: State-of-the-Art and Future Prospects

by Amgad Mohamed Elshoeibi 1,*, Ahmed Badr 1, Basel Elsayed 1, Omar Metwally 1, Raghad Elshoeibi 2, Mohamed Ragab Elhadary 1, Ahmed Elshoeibi 3, Mohamed Amro Attya 4, Fatima Khadadah 5, Awni Alshurafa 6, Ahmad Alhuraiji 5 and Mohamed Yassin 1,6,*
Reviewer 1:
Reviewer 2:
Reviewer 3: Anonymous
Submission received: 14 September 2023 / Revised: 24 October 2023 / Accepted: 27 October 2023 / Published: 22 December 2023
(This article belongs to the Section Cancer Causes, Screening and Diagnosis)

Round 1

Reviewer 1 Report

Comments and Suggestions for Authors

Any information about AI  contribution in differentiation of MDS with excess of blasts(<20%) from myelofibrosis.

Author Response

Please see the attachment

Author Response File: Author Response.pdf

Reviewer 2 Report

Comments and Suggestions for Authors

The study by Elshoeibi et al is a review of the litterature in thield of AI as  tool for diagnosis of MDS. The main question addressed by the paper is the state of the art of use of IA in diagnosis of MDS.

 The study described advantages and limitations of each published AI tools.

 The work is clear and documented.

A review of such area is very rare (AI in diagnosis of hematological malignancies). The originality is to analyse each published tool in term of advantages and limitations.

No other review deal with the subject, and the review itself is complete since most tool using AI are not yet published.

The references are appropriate, and the flow chart in the review is correctly described.

Comments on the Quality of English Language

No major comment.

Interesting and need minor editing of English.

Author Response

Please see the attachment

Author Response File: Author Response.pdf

Reviewer 3 Report

Comments and Suggestions for Authors Early diagnosis of MDS is of great importance to prevent it develoop into more aggressive disease and to improve current ways of diagnosing MDS. In this review, the authors summarized the state-of-the-art ML models for diagnosis of MDS.    Major comments:  
  1. it would nice to include one column in table 1 to indicate if the method is using PBS, BMS or FC.
  2. since different methods use different dataset to train their models and validate their results, i think the authors should have a section about the dataset used in reviewed models. The model performance is somehow related the dataset used in the model. To make fair comparison of different models, it’s better to use the same dataset. I suggest the authors to include the dataset info in table 2 so the authors know if the results are directly comparable or not.
Minor comment:   In line 115, foreign language is a bit confusing. I suggest the authors to change to “non-english”. The same in Figure 1, foreign language -> non-english.

Author Response

Please see the attachment

Author Response File: Author Response.pdf

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