Immunoglobulin Gene Sequence as an Inherited and Acquired Risk Factor for Chronic Lymphocytic Leukemia
Abstract
:Simple Summary
Abstract
1. Introduction
1.1. CLL Overview
1.2. Classification of CLL—Factors Affecting the CLL Prognosis
1.3. CLL Subsets
2. Importance of Light-Chain Sequence in CLL
3. Factors Affecting CLL-Cell Survival
4. Structural Basis of Autonomous Signaling
5. IGLV3-21R110G Defines a New Category of CLL
6. IGLV3-21*01/04 Are Potential Risk Alleles for Developing Aggressive CLL
7. Concluding Remarks
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Datta, M.; Jumaa, H. Immunoglobulin Gene Sequence as an Inherited and Acquired Risk Factor for Chronic Lymphocytic Leukemia. Cancers 2022, 14, 3045. https://doi.org/10.3390/cancers14133045
Datta M, Jumaa H. Immunoglobulin Gene Sequence as an Inherited and Acquired Risk Factor for Chronic Lymphocytic Leukemia. Cancers. 2022; 14(13):3045. https://doi.org/10.3390/cancers14133045
Chicago/Turabian StyleDatta, Moumita, and Hassan Jumaa. 2022. "Immunoglobulin Gene Sequence as an Inherited and Acquired Risk Factor for Chronic Lymphocytic Leukemia" Cancers 14, no. 13: 3045. https://doi.org/10.3390/cancers14133045