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Open AccessArticle

A Fluorescence-Based Wireless Capsule Endoscopy System for Detecting Colorectal Cancer

Departement of Electrical and Computer Engineering, University of Saskatchewan, Saskatoon, SK S7N 5A9, Canada
Author to whom correspondence should be addressed.
Cancers 2020, 12(4), 890;
Received: 19 February 2020 / Revised: 1 April 2020 / Accepted: 2 April 2020 / Published: 6 April 2020
(This article belongs to the Special Issue Non-Invasive Early Detection of Cancers)
Wireless capsule endoscopy (WCE) has been widely used in gastrointestinal (GI) diagnosis that allows the physicians to examine the interior wall of the human GI tract through a pain-free procedure. However, there are still several limitations of the technology, which limits its functionality, ultimately limiting its wide acceptance. Its counterpart, the wired endoscopic system is a painful procedure that demotivates patients from going through the procedure, and adversely affects early diagnosis. Furthermore, the current generation of capsules is unable to automate the detection of abnormality. As a result, physicians are required to spend longer hours to examine each image from the endoscopic capsule for abnormalities, which makes this technology tiresome and error-prone. Early detection of cancer is important to improve the survival rate in patients with colorectal cancer. Hence, a fluorescence-imaging-based endoscopic capsule that automates the detection process of colorectal cancer was designed and developed in our lab. The proof of concept of this endoscopic capsule was tested on porcine intestine and liquid phantom. The proposed WCE system offers great possibilities for future applicability in selective and specific detection of other fluorescently labelled cancers. View Full-Text
Keywords: wireless capsule endoscopy; fluorescence; colorectal cancer; non-invasive wireless capsule endoscopy; fluorescence; colorectal cancer; non-invasive
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Alam, M.W.; Vedaei, S.S.; Wahid, K.A. A Fluorescence-Based Wireless Capsule Endoscopy System for Detecting Colorectal Cancer. Cancers 2020, 12, 890.

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