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Cancers 2019, 11(2), 268; https://doi.org/10.3390/cancers11020268

Targeted Radionuclide Therapy: New Advances for Improvement of Patient Management and Response

CRUK/MRC Oxford Institute for Radiation Oncology, University of Oxford, Oxford OX37DQ, UK
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Received: 24 January 2019 / Revised: 20 February 2019 / Accepted: 21 February 2019 / Published: 25 February 2019
(This article belongs to the Special Issue New Developments in Radiotherapy)
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PDF [244 KB, uploaded 25 February 2019]

Abstract

Compared to external beam radiotherapy, targeted radionuclide therapy (TRT) allows for systemic radiation treatment of metastatic lesions. Published work on recent strategies to improve patient management and response to TRT through individualising patient treatment, modifying treatment pharmacokinetics and increasing anticancer potency are discussed in this review, with a special focus on the application of clinically evaluated radiolabelled ligands and peptides in the treatment of neuroendocrine and prostate cancers. View Full-Text
Keywords: patient management; precision medicine; targeted radionuclide therapy; prostate cancer; neuroendocrine cancer patient management; precision medicine; targeted radionuclide therapy; prostate cancer; neuroendocrine cancer
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Malcolm, J.; Falzone, N.; Lee, B.Q.; Vallis, K.A. Targeted Radionuclide Therapy: New Advances for Improvement of Patient Management and Response. Cancers 2019, 11, 268.

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