Quantitative, Multi-institutional Evaluation of MR Thermometry Accuracy for Deep-Pelvic MR-Hyperthermia Systems Operating in Multi-vendor MR-systems Using a New Anthropomorphic Phantom
Abstract
:1. Introduction
2. Methods and Materials
2.1. Phantom Development
2.2. QA Measurements
2.3. Data Analysis
3. Results
3.1. Influence of Cable Length
3.2. MRT vs. Thermistor Probe Measurements Evaluation
3.2.1. Centric Heating Target
3.2.2. Eccentric Heating Target
4. Discussion
5. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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Institution | Scan Type | TR (ms) | TE1 (ms) | TE2 (ms) | FA (deg) | Acquisition Matrix | Reconstruction Matrix | Scan Time (sec) |
---|---|---|---|---|---|---|---|---|
1 | High Resolution | 120 | 4.8 | 9.60 | 70 | 256/256 | 256/256 | 136 |
MRT | 620 | 4.8 | 19.1 | 40 | 128/128 | 256/256 | 83 | |
2 4 5 | High Resolution | 120 | 4.76 | 9.53 | 70 | 256/256 | 256/256 | 124 |
MRT | 600 | 4.76 | 19.10 | 50 | 128/128 | 128/128 | 78 | |
3 | High Resolution | 120 | 4.60 | 9.21 | 70 | 252/250 | 256/256 | 151 |
MRT | 600 | 4.60 | 18.42 | 50 | 128/128 | 256/256 | 79 |
Institution | Temperature Measurement | Mean Temperature Increase [ΔT (°C)] at Locations 1 to 4 | Mean Temperature Increase± SD (°C) | |||
---|---|---|---|---|---|---|
ΔT Location 1 | ΔT Location 2 | ΔT Location 3 | ΔT Location 4 | |||
1 | Thermistor probe | 4.7 | 4.6 | 5.2 | 5.3 | 5.0 ± 0.3 |
MRT | 3.8 | 3.5 | 4.3 | 4.3 | 4.0 ± 0.3 | |
2 | Thermistor probe | 6.8 | 4.7 | 5.6 | 5.6 | 5.7 ± 0.7 |
MRT | 6.2 | 4.9 | 5.3 | 5.1 | 5.4 ± 0.5 | |
3 | Thermistor probe | 4.4 | 4.2 | 4.4 | 4.3 | 4.3 ± 0.1 |
MRT | 3.6 | 3.2 | 3.7 | 3.5 | 3.5 ± 0.2 | |
4 | Thermistor probe | 4.1 | 4.1 | 3.9 | 4.0 | 4.0 ± 0.1 |
MRT | 3.2 | 3.9 | 3.5 | 3.3 | 3.5 ± 0.3 | |
5 | Thermistor probe | 3.2 | 3.4 | 4.0 | 4.2 | 3.7 ± 0.4 |
MRT | 2.3 | 2.4 | 3.0 | 3.3 | 2.7 ± 0.4 |
Institution | Temp. Measurem. | Mean Temperature Increase [ΔT (°C)] at Locations 1 to 4 | Mean Temp. Increase ± SD (°C) | d(ΔT Location 4- ΔT Location 1) (°C) | |||
---|---|---|---|---|---|---|---|
ΔT Location 1 | ΔT Location 2 | ΔT Location 3 | ΔT Location 4 | ||||
1 | Thermistor probe | 2.6 | 3.2 | 4.3 | 5.9 | 4.0 ± 1.2 | 3.3 |
MRT | 2.0 | 2.7 | 4.1 | 5.3 | 3.5 ± 1.3 | 3.3 | |
2 | Thermistor probe | 4.5 | 4.7 | 6.1 | 7.2 | 5.6 ± 1.1 | 2.7 |
MRT | 3.8 | 4.3 | 6.0 | 7.0 | 5.3 ± 1.3 | 3.2 | |
3 | Thermistor probe | 2.5 | 3.0 | 3.7 | 4.6 | 3.5 ± 0.8 | 2.1 |
MRT | 2.3 | 2.5 | 3.9 | 4.4 | 3.3 ± 0.9 | 2.0 | |
4 | Thermistor probe | 2.7 | 2.9 | 3.0 | 3.6 | 3.0 ± 0.3 | 0.9 |
MRT | 2.6 | 2.8 | 3.2 | 3.7 | 3.0 ± 0.4 | 1.1 | |
5 | Thermistor probe | 1.3 | 1.7 | 2.8 | 4.3 | 2.5 ± 1.2 | 3.0 |
MRT | 0.6 | 0.9 | 3.2 | 4.6 | 2.3 ± 1.6 | 3.9 |
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Curto, S.; Aklan, B.; Mulder, T.; Mils, O.; Schmidt, M.; Lamprecht, U.; Peller, M.; Wessalowski, R.; Lindner, L.H.; Fietkau, R.; et al. Quantitative, Multi-institutional Evaluation of MR Thermometry Accuracy for Deep-Pelvic MR-Hyperthermia Systems Operating in Multi-vendor MR-systems Using a New Anthropomorphic Phantom. Cancers 2019, 11, 1709. https://doi.org/10.3390/cancers11111709
Curto S, Aklan B, Mulder T, Mils O, Schmidt M, Lamprecht U, Peller M, Wessalowski R, Lindner LH, Fietkau R, et al. Quantitative, Multi-institutional Evaluation of MR Thermometry Accuracy for Deep-Pelvic MR-Hyperthermia Systems Operating in Multi-vendor MR-systems Using a New Anthropomorphic Phantom. Cancers. 2019; 11(11):1709. https://doi.org/10.3390/cancers11111709
Chicago/Turabian StyleCurto, Sergio, Bassim Aklan, Tim Mulder, Oliver Mils, Manfred Schmidt, Ulf Lamprecht, Michael Peller, Ruediger Wessalowski, Lars H. Lindner, Rainer Fietkau, and et al. 2019. "Quantitative, Multi-institutional Evaluation of MR Thermometry Accuracy for Deep-Pelvic MR-Hyperthermia Systems Operating in Multi-vendor MR-systems Using a New Anthropomorphic Phantom" Cancers 11, no. 11: 1709. https://doi.org/10.3390/cancers11111709