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Review

Micelles Structure Development as a Strategy to Improve Smart Cancer Therapy

1
Sohag Cancer Center, Sohag 82511, Egypt
2
Institute of Nanoscience and Nanotechnology, Kafrelsheikh University, Kafrelsheikh 33516, Egypt
3
CNR NANOTEC-Istituto di Nanotecnologia, 73100 Lecce, Italy
*
Author to whom correspondence should be addressed.
Cancers 2018, 10(7), 238; https://doi.org/10.3390/cancers10070238
Received: 8 June 2018 / Revised: 12 July 2018 / Accepted: 17 July 2018 / Published: 20 July 2018
(This article belongs to the Special Issue Nanotechnology and Cancer)
Micelles as colloidal suspension have attracted considerable attention due to their potential use for both cancer diagnosis and therapy. These structures have proven their ability to deliver poorly water-soluble anticancer drugs, improve drug stability, and have good penetration and site-specificity, leading to enhance therapeutic efficacy. Micelles are composed of hydrophobic and hydrophilic components assembled into nanosized spherical, ellipsoid, cylindrical, or unilamellar structures. For their simple formation, they are widely studied, either by using opposite polymers attachment consisting of two or more block copolymers, or by using fatty acid molecules that can modify themselves in a rounded shape. Recently, hybrid and responsive stimuli nanomicelles are formed either by integration with metal nanoparticles such as silver, gold, iron oxide nanoparticles inside micelles or by a combination of lipids and polymers into single composite. Herein, through this special issue, an updated overview of micelles development and their application for cancer therapy will be discussed. View Full-Text
Keywords: micelles; hybrid polymeric and stimuli-responsive nanomicelles; cancer therapy micelles; hybrid polymeric and stimuli-responsive nanomicelles; cancer therapy
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MDPI and ACS Style

Hanafy, N.A.N.; El-Kemary, M.; Leporatti, S. Micelles Structure Development as a Strategy to Improve Smart Cancer Therapy. Cancers 2018, 10, 238. https://doi.org/10.3390/cancers10070238

AMA Style

Hanafy NAN, El-Kemary M, Leporatti S. Micelles Structure Development as a Strategy to Improve Smart Cancer Therapy. Cancers. 2018; 10(7):238. https://doi.org/10.3390/cancers10070238

Chicago/Turabian Style

Hanafy, Nemany A.N., Maged El-Kemary, and Stefano Leporatti. 2018. "Micelles Structure Development as a Strategy to Improve Smart Cancer Therapy" Cancers 10, no. 7: 238. https://doi.org/10.3390/cancers10070238

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