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Open AccessArticle

Simulation, Fabrication and Analysis of Silver Based Ascending Sinusoidal Microchannel (ASMC) for Implant of Varicose Veins

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Department of Physics, The University of Lahore, Lahore 54000, Pakistan
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Department of Computer Engineering, The University of Lahore, Lahore 54000, Pakistan
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Department of Physics (Electronics), GC University, Lahore 54000, Pakistan
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Institute of Electronics, Atomic Energy Research Establishment, Bangladesh Atomic Energy Commission, Dhaka 1349, Bangladesh
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Department of Applied Physics, Electronics and Communication Engineering; Islamic University, Khustia 7003, Bangladesh
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Department of Mechanical Engineering Technology (MCET), Higher Colleges of Technology (HCT), Ras al-Khaimah POBox 4793, UAE
*
Author to whom correspondence should be addressed.
Micromachines 2017, 8(9), 278; https://doi.org/10.3390/mi8090278
Received: 6 June 2017 / Revised: 30 August 2017 / Accepted: 4 September 2017 / Published: 14 September 2017
(This article belongs to the Special Issue Medical Microdevices and Micromachines)
Bioengineered veins can benefit humans needing bypass surgery, dialysis, and now, in the treatment of varicose veins. The implant of this vein in varicose veins has significant advantages over the conventional treatment methods. Deep vein thrombosis (DVT), vein patch repair, pulmonary embolus, and tissue-damaging problems can be solved with this implant. Here, the authors have proposed biomedical microdevices as an alternative for varicose veins. MATLAB and ANSYS Fluent have been used for simulations of blood flow for bioengineered veins. The silver based microchannel has been fabricated by using a micromachining process. The dimensions of the silver substrates are 51 mm, 25 mm, and 1.1 mm, in length, width, and depth respectively. The dimensions of microchannels grooved in the substrates are 0.9 mm in width and depth. The boundary conditions for pressure and velocity were considered, from 1.0 kPa to 1.50 kPa, and 0.02 m/s to 0.07 m/s, respectively. These are the actual values of pressure and velocity in varicose veins. The flow rate of 5.843 (0.1 nL/s) and velocity of 5.843 cm/s were determined at Reynolds number 164.88 in experimental testing. The graphs and results from simulations and experiments are in close agreement. These microchannels can be inserted into varicose veins as a replacement to maintain the excellent blood flow in human legs. View Full-Text
Keywords: ANSYS; bioengineered vein; bioMEMS; fuzzy logic; microfluidics; microchannels; varicose vein ANSYS; bioengineered vein; bioMEMS; fuzzy logic; microfluidics; microchannels; varicose vein
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Afzal, M.J.; Tayyaba, S.; Ashraf, M.W.; Hossain, M.K.; Uddin, M.J.; Afzulpurkar, N. Simulation, Fabrication and Analysis of Silver Based Ascending Sinusoidal Microchannel (ASMC) for Implant of Varicose Veins. Micromachines 2017, 8, 278.

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