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Review

Lateral Flow Immunoassays for Detecting Viral Infectious Antigens and Antibodies

by
Rowa Y. Alhabbab
1,2
1
Vaccines and Immunotherapy Unit, King Fahad Medical Research Center, King Abdulaziz University, Jeddah 21589, Saudi Arabia
2
Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia
Micromachines 2022, 13(11), 1901; https://doi.org/10.3390/mi13111901
Submission received: 15 September 2022 / Revised: 14 October 2022 / Accepted: 19 October 2022 / Published: 3 November 2022
(This article belongs to the Special Issue Fast Bio-Chemical Test)

Abstract

Abundant immunological assays currently exist for detecting pathogens and identifying infected individuals, making detection of diseases at early stages integral to preventing their spread, together with the consequent emergence of global health crises. Lateral flow immunoassay (LFIA) is a test characterized by simplicity, low cost, and quick results. Furthermore, LFIA testing does not need well-trained individuals or laboratory settings. Therefore, it has been serving as an attractive tool that has been extensively used during the ongoing COVID-19 pandemic. Here, the LFIA strip’s available formats, reporter systems, components, and preparation are discussed. Moreover, this review provides an overview of the current LFIAs in detecting infectious viral antigens and humoral responses to viral infections.
Keywords: lateral flow immunoassay; viral infections; diagnostic tool; antigen detection; antibodies detection lateral flow immunoassay; viral infections; diagnostic tool; antigen detection; antibodies detection

Share and Cite

MDPI and ACS Style

Alhabbab, R.Y. Lateral Flow Immunoassays for Detecting Viral Infectious Antigens and Antibodies. Micromachines 2022, 13, 1901. https://doi.org/10.3390/mi13111901

AMA Style

Alhabbab RY. Lateral Flow Immunoassays for Detecting Viral Infectious Antigens and Antibodies. Micromachines. 2022; 13(11):1901. https://doi.org/10.3390/mi13111901

Chicago/Turabian Style

Alhabbab, Rowa Y. 2022. "Lateral Flow Immunoassays for Detecting Viral Infectious Antigens and Antibodies" Micromachines 13, no. 11: 1901. https://doi.org/10.3390/mi13111901

APA Style

Alhabbab, R. Y. (2022). Lateral Flow Immunoassays for Detecting Viral Infectious Antigens and Antibodies. Micromachines, 13(11), 1901. https://doi.org/10.3390/mi13111901

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