Next Article in Journal
Growth of Less than 20 nm SnO Nanowires Using an Anodic Aluminum Oxide Template for Gas Sensing
Previous Article in Journal
A Quantitative Study of the Secondary Acoustic Radiation Force on Biological Cells during Acoustophoresis
Open AccessArticle

High-Efficiency Small Sample Microparticle Fractionation on a Femtosecond Laser-Machined Microfluidic Disc

1
NanoLab, School of Applied Technical Sciences, German Jordanian University (GJU), Amman 11180, Jordan
2
Institut für Mikrotechnik, Technische Universität Braunschweig, 38124 Braunschweig, Germany
3
Faculty of Engineering, Middle East University, Amman 11831, Jordan
*
Author to whom correspondence should be addressed.
Micromachines 2020, 11(2), 151; https://doi.org/10.3390/mi11020151
Received: 18 December 2019 / Revised: 24 January 2020 / Accepted: 27 January 2020 / Published: 30 January 2020
(This article belongs to the Special Issue Inertial Microfluidics)
The fabrication and testing of microfluidic spinning compact discs with embedded trapezoidal microchambers for the purpose of inertial microparticle focusing is reported in this article. Microparticle focusing channels require small features that cannot be easily fabricated in acrylic sheets and are complicated to realize in glass by traditional lithography techniques; therefore, the fabrication of microfluidic discs with femtosecond laser ablation is reported for the first time in this paper. It could be demonstrated that high-efficiency inertial focusing of 5 and 10 µm particles is achieved in a channel with trapezoidal microchambers regardless of the direction of disc rotation, which correlates to the dominance of inertial forces over Coriolis forces. To achieve the highest throughput possible, the suspension concentration was increased from 0.001% (w/v) to 0.005% (w/v). The focusing efficiency was 98.7% for the 10 µm particles and 93.75% for the 5 µm particles.
Keywords: microfluidics; femtosecond laser; microparticle separation; microfluidic disc microfluidics; femtosecond laser; microparticle separation; microfluidic disc
Show Figures

Graphical abstract

MDPI and ACS Style

Al-Halhouli, A.; Doofesh, Z.; Albagdady, A.; Dietzel, A. High-Efficiency Small Sample Microparticle Fractionation on a Femtosecond Laser-Machined Microfluidic Disc. Micromachines 2020, 11, 151.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop