High-Efficiency Small Sample Microparticle Fractionation on a Femtosecond Laser-Machined Microfluidic Disc
1
NanoLab, School of Applied Technical Sciences, German Jordanian University (GJU), Amman 11180, Jordan
2
Institut für Mikrotechnik, Technische Universität Braunschweig, 38124 Braunschweig, Germany
3
Faculty of Engineering, Middle East University, Amman 11831, Jordan
*
Author to whom correspondence should be addressed.
Micromachines 2020, 11(2), 151; https://doi.org/10.3390/mi11020151
Received: 18 December 2019 / Revised: 24 January 2020 / Accepted: 27 January 2020 / Published: 30 January 2020
(This article belongs to the Special Issue Inertial Microfluidics)
The fabrication and testing of microfluidic spinning compact discs with embedded trapezoidal microchambers for the purpose of inertial microparticle focusing is reported in this article. Microparticle focusing channels require small features that cannot be easily fabricated in acrylic sheets and are complicated to realize in glass by traditional lithography techniques; therefore, the fabrication of microfluidic discs with femtosecond laser ablation is reported for the first time in this paper. It could be demonstrated that high-efficiency inertial focusing of 5 and 10 µm particles is achieved in a channel with trapezoidal microchambers regardless of the direction of disc rotation, which correlates to the dominance of inertial forces over Coriolis forces. To achieve the highest throughput possible, the suspension concentration was increased from 0.001% (w/v) to 0.005% (w/v). The focusing efficiency was 98.7% for the 10 µm particles and 93.75% for the 5 µm particles.
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MDPI and ACS Style
Al-Halhouli, A.; Doofesh, Z.; Albagdady, A.; Dietzel, A. High-Efficiency Small Sample Microparticle Fractionation on a Femtosecond Laser-Machined Microfluidic Disc. Micromachines 2020, 11, 151. https://doi.org/10.3390/mi11020151
AMA Style
Al-Halhouli A, Doofesh Z, Albagdady A, Dietzel A. High-Efficiency Small Sample Microparticle Fractionation on a Femtosecond Laser-Machined Microfluidic Disc. Micromachines. 2020; 11(2):151. https://doi.org/10.3390/mi11020151
Chicago/Turabian StyleAl-Halhouli, Ala’aldeen; Doofesh, Zaid; Albagdady, Ahmed; Dietzel, Andreas. 2020. "High-Efficiency Small Sample Microparticle Fractionation on a Femtosecond Laser-Machined Microfluidic Disc" Micromachines 11, no. 2: 151. https://doi.org/10.3390/mi11020151
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