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Open AccessArticle

Application of a Terahertz System Combined with an X-Shaped Metamaterial Microfluidic Cartridge

Department of Power Mechanical Engineering, National Tsing Hua University, Hsinchu 30013, Taiwan
ACE BIOTEK Co. Ltd., Hsinchu 30261, Taiwan
Department of Material Science Engineering, National Tsing Hua University, Hsinchu 30013, Taiwan
Institute of NanoEngineering and MicroSystems, National Tsing Hua University, Hsinchu 30013, Taiwan
Author to whom correspondence should be addressed.
Micromachines 2020, 11(1), 74;
Received: 17 December 2019 / Revised: 4 January 2020 / Accepted: 5 January 2020 / Published: 9 January 2020
(This article belongs to the Special Issue 10th Anniversary of Micromachines)
Terahertz (THz) radiation has attracted wide attention for its ability to sense molecular structure and chemical matter because of a label-free molecular fingerprint and nondestructive properties. When it comes to molecular recognition with terahertz radiation, our attention goes first towards the absorption spectrum, which is beyond the far infrared region. To enhance the sensitivity for similar species, however, it is necessary to apply an artificially designed metamaterial sensor for detection, which confines an electromagnetic field in an extremely sub-wavelength space and hence receives an electromagnetic response through resonance. Once the resonance is caused through the interaction between the THz radiation and the metamaterial, a minute variation might be observed in the frequency domain. For a geometric structure of a metamaterial, a novel design called an X-shaped plasmonic sensor (XPS) can create a quadrupole resonance and lead to sensitivity greater than in the dipole mode. A microfluidic system is able to consume reagents in small volumes for detection, to diminish noise from the environment, and to concentrate the sample into detection spots. A microfluidic device integrated with an X-shaped plasmonic sensor might thus achieve an effective and highly sensitive detection cartridge. Our tests involved not only measurements of liquid samples, but also the performance of a dry bio-sample coated on an XPS. View Full-Text
Keywords: terahertz radiation; metamaterials; microfluidics terahertz radiation; metamaterials; microfluidics
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Huang, S.-T.; Hsu, S.-F.; Tang, K.-Y.; Yen, T.-J.; Yao, D.-J. Application of a Terahertz System Combined with an X-Shaped Metamaterial Microfluidic Cartridge. Micromachines 2020, 11, 74.

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