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Open AccessReview

DEP-on-a-Chip: Dielectrophoresis Applied to Microfluidic Platforms

by 1, 1,* and 1,2,3,*
1
Ministry of Education Key Laboratory of Micro/Nano Systems for Aerospace, School of Mechanical Engineering, Northwestern Polytechnical University, 127 West Youyi Road, Xi’an 710072, China
2
Central European Institute of Technology, Brno University of Technology, Brno 61300, Czech Republic
3
Department of Microelectronics, Faculty of Electrical Engineering, Brno University of Technology, Technická 3058/10, Brno 61600, Czech Republic
*
Authors to whom correspondence should be addressed.
Micromachines 2019, 10(6), 423; https://doi.org/10.3390/mi10060423
Received: 17 May 2019 / Revised: 15 June 2019 / Accepted: 19 June 2019 / Published: 24 June 2019
(This article belongs to the Special Issue Nanoparticles on Microfluidic Platforms)
Dielectric particles in a non-uniform electric field are subject to a force caused by a phenomenon called dielectrophoresis (DEP). DEP is a commonly used technique in microfluidics for particle or cell separation. In comparison with other separation methods, DEP has the unique advantage of being label-free, fast, and accurate. It has been widely applied in microfluidics for bio-molecular diagnostics and medical and polymer research. This review introduces the basic theory of DEP, its advantages compared with other separation methods, and its applications in recent years, in particular, focusing on the different electrode types integrated into microfluidic chips, fabrication techniques, and operation principles. View Full-Text
Keywords: dielectrophoresis; microfluidics; two-dimensional electrodes; parallel electrodes; interdigitated electrode; castellated electrodes; three-dimensional electrodes dielectrophoresis; microfluidics; two-dimensional electrodes; parallel electrodes; interdigitated electrode; castellated electrodes; three-dimensional electrodes
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MDPI and ACS Style

Zhang, H.; Chang, H.; Neuzil, P. DEP-on-a-Chip: Dielectrophoresis Applied to Microfluidic Platforms. Micromachines 2019, 10, 423. https://doi.org/10.3390/mi10060423

AMA Style

Zhang H, Chang H, Neuzil P. DEP-on-a-Chip: Dielectrophoresis Applied to Microfluidic Platforms. Micromachines. 2019; 10(6):423. https://doi.org/10.3390/mi10060423

Chicago/Turabian Style

Zhang, Haoqing; Chang, Honglong; Neuzil, Pavel. 2019. "DEP-on-a-Chip: Dielectrophoresis Applied to Microfluidic Platforms" Micromachines 10, no. 6: 423. https://doi.org/10.3390/mi10060423

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