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Micromachines 2019, 10(1), 27; https://doi.org/10.3390/mi10010027

Handheld Inkjet Printing Paper Chip Based Smart Tetracycline Detector

1
Joint International Research Laboratory of Animal Health and Food Safety of Ministry of Education & Single Molecule Nanometry Laboratory (Sinmolab), Nanjing Agricultural University, Nanjing 210095, Jiangsu, China
2
School of Manufacturing Science and Engineering, Southwest University of Science and Technology, Mianyang 621010, Sichuan, China
3
Computational Optics Laboratory, School of Science, Jiangnan University, Wuxi 214122, Jiangsu, China
4
College of Electronics and Information Engineering, Shanghai University of Electric Power, Shanghai 200090, China
*
Authors to whom correspondence should be addressed.
Received: 25 November 2018 / Revised: 20 December 2018 / Accepted: 27 December 2018 / Published: 1 January 2019
(This article belongs to the Special Issue Miniature Mobile Imaging and Sensing Devices)
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Abstract

Tetracycline is widely used as medicine for disease treatments and additives in animal feeding. Unfortunately, the abuse of tetracycline inevitably causes tetracycline residue in animal-origin foods. Though classical methods can detect tetracycline in high sensitivity and precision, they often rely on huge and expensive setups as well as complicated and time-consuming operations, limiting their applications in rapid and on-site detection. Here, we propose a handheld inkjet printing paper chip based smart tetracycline detector: tetracycline can be determined by inkjet printing prepared paper chip based enzyme-linked immunosorbent assay (ELISA) with the advantages of high sensitivity, excellent specificity and low cost; moreover, a smartphone based paper chip reader and application is designed for automatically determining tetracycline with simple operations, high precision and fast speed. The smart tetracycline detector with a compact size of 154 mm × 80 mm × 50 mm and self-supplied internal power can reach a rather low detection limit of ~0.05 ng/mL, as proved by practical measurements. It is believed the proposed handheld inkjet printing paper chip based smart tetracycline detector is a potential tool in antibiotic sensing for routine uses at home and on-site detection in the field. View Full-Text
Keywords: smart tetracycline detector; inkjet printing paper chip; on-site detection smart tetracycline detector; inkjet printing paper chip; on-site detection
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Li, J.; Wang, X.; Shan, Y.; Huang, H.; Jian, D.; Xue, L.; Wang, S.; Liu, F. Handheld Inkjet Printing Paper Chip Based Smart Tetracycline Detector. Micromachines 2019, 10, 27.

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