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Mycotoxin Occurrence, Toxicity, and Detoxifying Agents in Pig Production with an Emphasis on Deoxynivalenol

Department of Animal Science, North Carolina State University, Raleigh, NC 27695, USA
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Toxins 2021, 13(2), 171; https://doi.org/10.3390/toxins13020171
Received: 5 February 2021 / Revised: 16 February 2021 / Accepted: 18 February 2021 / Published: 23 February 2021
This review aimed to investigate the occurrence of mycotoxins, their toxic effects, and the detoxifying agents discussed in scientific publications that are related to pig production. Mycotoxins that are of major interest are aflatoxins and Fusarium toxins, such as deoxynivalenol and fumonisins, because of their elevated frequency at a global scale and high occurrence in corn, which is the main feedstuff in pig diets. The toxic effects of aflatoxins, deoxynivalenol, and fumonisins include immune modulation, disruption of intestinal barrier function, and cytotoxicity leading to cell death, which all result in impaired pig performance. Feed additives, such as mycotoxin-detoxifying agents, that are currently available often combine organic and inorganic sources to enhance their adsorbability, immune stimulation, or ability to render mycotoxins less toxic. In summary, mycotoxins present challenges to pig production globally because of their increasing occurrences in recent years and their toxic effects impairing the health and growth of pigs. Effective mycotoxin-detoxifying agents must be used to boost pig health and performance and to improve the sustainable use of crops. View Full-Text
Keywords: aflatoxin; deoxynivalenol; mycotoxin detoxification; fumonisin; mycotoxin frequency; mycotoxin toxicity; pig aflatoxin; deoxynivalenol; mycotoxin detoxification; fumonisin; mycotoxin frequency; mycotoxin toxicity; pig
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MDPI and ACS Style

Holanda, D.M.; Kim, S.W. Mycotoxin Occurrence, Toxicity, and Detoxifying Agents in Pig Production with an Emphasis on Deoxynivalenol. Toxins 2021, 13, 171. https://doi.org/10.3390/toxins13020171

AMA Style

Holanda DM, Kim SW. Mycotoxin Occurrence, Toxicity, and Detoxifying Agents in Pig Production with an Emphasis on Deoxynivalenol. Toxins. 2021; 13(2):171. https://doi.org/10.3390/toxins13020171

Chicago/Turabian Style

Holanda, Debora M.; Kim, Sung W. 2021. "Mycotoxin Occurrence, Toxicity, and Detoxifying Agents in Pig Production with an Emphasis on Deoxynivalenol" Toxins 13, no. 2: 171. https://doi.org/10.3390/toxins13020171

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