Next Article in Journal
Vitamin C Intake is Inversely Associated with Cardiovascular Mortality in a Cohort of Spanish Graduates: the SUN Project
Next Article in Special Issue
Low Docosahexaenoic Acid, Dihomo-Gamma-Linolenic Acid, and Arachidonic Acid Levels Associated with Long-Term Mortality in Patients with Acute Decompensated Heart Failure in Different Nutritional Statuses
Previous Article in Journal
Effects of Simulated Human Gastrointestinal Digestion of Two Purple-Fleshed Potato Cultivars on Anthocyanin Composition and Cytotoxicity in Colonic Cancer and Non-Tumorigenic Cells
Previous Article in Special Issue
Omega 3 Polyunsaturated Fatty Acids Improve Endothelial Dysfunction in Chronic Renal Failure: Role of eNOS Activation and of Oxidative Stress
Open AccessArticle

Dietary Fish and Long-Chain n-3 Polyunsaturated Fatty Acids Intake and Risk of Atrial Fibrillation: A Meta-Analysis

by Fu-Rong Li 1,†, Guo-Chong Chen 2,3,†, 4 and Xianbo Wu 1,*
1
Department of Epidemiology, School of Public Health, Southern Medical University, Guangzhou 510000, Guangdong, China
2
Department of Nutrition and Food Hygiene, School of Public Health, Soochow University, Suzhou 215000, Jiangsu, China
3
Saw Swee Hock School of Public Health, National University of Singapore, Singapore 546080, Singapore
4
Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, 110 Xiangya Road, Changsha 410078, Hunan , China
*
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Nutrients 2017, 9(9), 955; https://doi.org/10.3390/nu9090955
Received: 2 July 2017 / Revised: 16 August 2017 / Accepted: 25 August 2017 / Published: 29 August 2017
(This article belongs to the Special Issue Omega-3 Polyunsaturated Fatty Acids and Cardiovascular Health)
Findings on the association between long-term intake of fish or long-chain n-3 polyunsaturated fatty acids (PUFAs) and risk of atrial fibrillation (AF) are inconsistent in observational studies. We conducted a meta-analysis of prospective studies to separately examine the associations between fish consumption and dietary intake of n-3 PUFAs with the risk of AF. A systematic search was conducted in PubMed and Embase to identify relevant studies. Risk estimates were combined using a random-effect model. Seven prospective cohort studies covering 206,811 participants and 12,913 AF cases were eligible. The summary relative risk of AF for the highest vs. lowest category of fish consumption and dietary intake of n-3 PUFAs was 1.01(95% confidence interval: 0.94–1.09) and 1.03 (95% confidence interval: 0.97–1.09), respectively. These null associations persisted in subgroup and dose-response analyses. There was little evidence of publication bias. This meta-analysis suggests that neither long-term intake of fish, nor of n-3 PUFAs were significantly associated with lower risk of AF. View Full-Text
Keywords: fish; n-3 polyunsaturated fatty acids; atrial fibrillation; meta-analysis fish; n-3 polyunsaturated fatty acids; atrial fibrillation; meta-analysis
Show Figures

Figure 1

MDPI and ACS Style

Li, F.-R.; Chen, G.-C.; Qin, J.; Wu, X. Dietary Fish and Long-Chain n-3 Polyunsaturated Fatty Acids Intake and Risk of Atrial Fibrillation: A Meta-Analysis. Nutrients 2017, 9, 955.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop