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Open AccessLetter

Complementary Intradermal and Patch Testing for Increased Diagnostic Accuracy of Nickel Allergy in Non-Celiac Wheat Insensitivity

Department of Dermatology, Loma Linda University, 11370 Anderson Street, Suite 2600, Loma Linda, CA 92354, USA
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Nutrients 2017, 9(6), 536; https://doi.org/10.3390/nu9060536
Received: 12 May 2017 / Revised: 16 May 2017 / Accepted: 22 May 2017 / Published: 24 May 2017
D’Alcamo et al. astutely highlighted a potential immunologic association between nickel allergy, determined by positive epicutaneous patch testing, and the rise of non-celiac wheat sensitivity (NCWS) in the world of gluten-related diseases. Consecutive algorithms including both patch and intradermal testing could provide vital information to more accurately define the patient populations with NCWS, systemic nickel allergy syndrome, and nickel-associated allergic contact dermatitis. View Full-Text
Keywords: non-celiac wheat insensitivity; nickel; systemic nickel allergy syndrome; intradermal testing non-celiac wheat insensitivity; nickel; systemic nickel allergy syndrome; intradermal testing
MDPI and ACS Style

Limone, B.A.; Rasmussen, A.; Kwon, S.M.; Jacob, S.E. Complementary Intradermal and Patch Testing for Increased Diagnostic Accuracy of Nickel Allergy in Non-Celiac Wheat Insensitivity. Nutrients 2017, 9, 536.

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