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Vitamin D Intake and Status in 6-Year-Old Icelandic Children Followed up from Infancy

1
Unit for Nutrition Research, Faculty of Food Science and Nutrition, School of Health Sciences, University of Iceland and Landspitali University Hospital, Reykjavik 101, Iceland
2
Children’s Hospital, Landspitali University Hospital, Reykjavik 101, Iceland
*
Author to whom correspondence should be addressed.
Nutrients 2016, 8(2), 75; https://doi.org/10.3390/nu8020075
Received: 23 October 2015 / Revised: 12 January 2016 / Accepted: 27 January 2016 / Published: 4 February 2016
High serum 25-hydroxyvitamin D (25(OH)D) levels have been observed in infants in Nordic countries, likely due to vitamin D supplement use. Internationally, little is known about tracking vitamin D status from infancy to childhood. Following up 1-year-old infants in our national longitudinal cohort, our aims were to study vitamin D intake and status in healthy 6-year-old Icelandic children (n = 139) and to track vitamin D status from one year of age. At six years, the mean 25(OH)D level was 56.5 nmol/L (SD 17.9) and 64% of children were vitamin D sufficient (25(OH)D ≥ 50 nmol/L). A logistic regression model adjusted for gender and breastfeeding showed that higher total vitamin D intake (Odds ratio (OR) = 1.27, 95% confidence interval (CI) = 1.08–1.49), blood samples collected in summer (OR = 8.88, 95% CI = 1.83–43.23) or autumn (OR = 5.64, 95% CI = 1.16–27.32) compared to winter/spring, and 25(OH)D at age one (OR = 1.02, 95% CI = 1.002–1.04) were independently associated with vitamin D sufficiency at age six. The correlation between 25(OH)D at age one and six was 0.34 (p = 0.003). Our findings suggest that vitamin D status in infancy, current vitamin D intake and season are predictors of vitamin D status in early school age children. Our finding of vitamin D status tracking from infancy to childhood provides motivation for further studies on tracking and its clinical significance. View Full-Text
Keywords: 25-hydroxyvitamin D; child; dietary supplements; seasons; tracking; vitamin D 25-hydroxyvitamin D; child; dietary supplements; seasons; tracking; vitamin D
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Thorisdottir, B.; Gunnarsdottir, I.; Steingrimsdottir, L.; Palsson, G.I.; Birgisdottir, B.E.; Thorsdottir, I. Vitamin D Intake and Status in 6-Year-Old Icelandic Children Followed up from Infancy. Nutrients 2016, 8, 75.

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