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Nutrients 2013, 5(7), 2405-2456;

Diminishing Risk for Age-Related Macular Degeneration with Nutrition: A Current View

Laboratory for Nutrition and Vision Research, JM USDA Human Nutrition Research Center on Aging Tufts University, 711 Washington St, Boston, MA 02111, USA
Boston Medical Center, 650 Albany Street, Boston, MA 02118, USA
Author to whom correspondence should be addressed.
Received: 27 May 2013 / Revised: 24 June 2013 / Accepted: 24 June 2013 / Published: 2 July 2013
(This article belongs to the Special Issue Nutrition and the Eye)


Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly. Clinical hallmarks of AMD are observed in one third of the elderly in industrialized countries. Preventative interventions through dietary modification are attractive strategies, because they are more affordable than clinical therapies, do not require specialists for administration and many studies suggest a benefit of micro- and macro-nutrients with respect to AMD with few, if any, adverse effects. The goal of this review is to provide information from recent literature on the value of various nutrients, particularly omega-3 fatty acids, lower glycemic index diets and, perhaps, some carotenoids, with regard to diminishing risk for onset or progression of AMD. Results from the upcoming Age-Related Eye Disease Study (AREDS) II intervention trial should be particularly informative. View Full-Text
Keywords: AMD; antioxidants; carotenoids; nutrition; glycemic index; aging AMD; antioxidants; carotenoids; nutrition; glycemic index; aging

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This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Schleicher, M.; Weikel, K.; Garber, C.; Taylor, A. Diminishing Risk for Age-Related Macular Degeneration with Nutrition: A Current View. Nutrients 2013, 5, 2405-2456.

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