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Effects of Collagen and Collagen Hydrolysate from Jellyfish Umbrella on Histological and Immunity Changes of Mice Photoaging

1
College of Chemistry and Engineering, Kunming University of Science and Technology, Kunming, 650500, Yunnan, China
2
Department of Food Chemistry and Nutrition, College of Food Science and Engineering, Ocean University of China, Qingdao 266003, Shandong, China
*
Author to whom correspondence should be addressed.
Nutrients 2013, 5(1), 223-233; https://doi.org/10.3390/nu5010223
Received: 2 November 2012 / Revised: 17 December 2012 / Accepted: 4 January 2013 / Published: 17 January 2013
Jellyfish collagen (JC) was extracted from jellyfish umbrella and hydrolyzed to prepare jellyfish collagen hydrolysate (JCH). The effects of JC and JCH on UV-induced skin damage of mice were evaluated by the skin moisture, microscopic analyses of skin and immunity indexes. The skin moisture analyses showed that moisture retention ability of UV-induced mice skin was increased by JC and JCH. Further histological analysis showed that JC and JCH could repair the endogenous collagen and elastin protein fibers, and could maintain the natural ratio of type I to type III collagen. The immunity indexes showed that JC and JCH play a role in enhancing immunity of photoaging mice in vivo. JCH showed much higher protective ability than JC. These results suggest that JCH as a potential novel antiphotoaging agent from natural resources. View Full-Text
Keywords: jellyfish; collagen; photoaging; histological analysis; immunity jellyfish; collagen; photoaging; histological analysis; immunity
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Fan, J.; Zhuang, Y.; Li, B. Effects of Collagen and Collagen Hydrolysate from Jellyfish Umbrella on Histological and Immunity Changes of Mice Photoaging. Nutrients 2013, 5, 223-233.

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