An Exploratory Study of Serum 25-Hydroxyvitamin D Concentration and Psychological Distress Among Aboriginal and Torres Strait Islander Peoples in Australia
Abstract
1. Introduction
2. Materials and Methods
2.1. Project Governance
2.2. Study Population
2.3. Covariates
2.4. Psychological Distress
2.5. Measurement of Serum 25(OH)D Concentration
2.6. Statistical Analysis
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
Abbreviations
| 25(OH)D | 25-hydroxyvitamin D |
| AATSIHS | Australian Aboriginal and Torres Strait Islander Health Survey |
| ABS | Australian Bureau of Statistics |
| K5 | Kessler Psychological Distress Scale 5 |
| LC-MS/MS | Liquid Chromatography with Tandem Mass Spectrometry |
| NATSIHS | National Aboriginal and Torres Strait Islander Health Survey |
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| Characteristics | Results |
|---|---|
| Age (years), median (25th, 75th percentile) | 36 (26, 48) |
| Sex, n (%) | |
| Male | 799 (48.6) |
| Female | 1184 (51.4) |
| Serum 25(OH)D concentration (nmol/L), mean (SD) | 64.0 (22.2) |
| Category of 25(OH)D, n (%) 2 | |
| 25(OH)D ≥ 50 nmol/L | 1272 (72.2) |
| 25(OH)D 30–49 nmol/L | 575 (22.8) |
| 25(OH)D < 30 nmol/L | 136 (5.0) |
| K5 score, median (25th, 75th percentile) | 9 (6, 13) |
| Category of K5, n (%) 2 | |
| Low/moderate psychological distress (5–11) | 1386 (68.5) |
| High/very high psychological distress (12–25) | 597 (31.5) |
| Smoking status, n (%) | |
| Ex/non-smoker | 1117 (64.2) |
| Current smoker | 866 (35.8) |
| Alcohol intake, median (25th, 75th percentile) 3 | 0.5 (0, 5.8) |
| Education, n (%) | |
| No/primary/high school | 1164 (51.3) |
| Diploma/certificate | 681 (42.0) |
| University | 138 (6.7) |
| Socioeconomic status, n (%) | |
| Quintile 1 | 1187 (48.5) |
| Quintile 2 | 348 (23.0) |
| Quintile 3 | 200 (12.2) |
| Quintile 4 | 181 (12.6) |
| Quintile 5 | 67 (3.7) |
| Remoteness, n (%) | |
| Non-remote | 915 (77.8) |
| Remote | 1068 (22.2) |
| Season of blood collection, n (%) | |
| Summer | 392 (27.8) |
| Autumn | 110 (9.4) |
| Winter | 529 (24.5) |
| Spring | 952 (38.3) |
| Unadjusted | Adjusted 2 | |||||||
|---|---|---|---|---|---|---|---|---|
| β | OR | 95% CI | p-Value | Adj. β | Adj. OR | 95% CI | p-Value | |
| Total population (n = 1983) | −0.07 | 0.93 | −0.16, 0.02 | 0.119 | −0.08 | 0.92 | −0.17, 0.01 | 0.088 |
| Stratified by sex: | ||||||||
| Male (n = 799) | −0.06 | 0.94 | −0.21, 0.09 | 0.457 | −0.02 | 0.98 | −0.17, 0.13 | 0.805 |
| Female (n = 1184) | −0.08 | 0.92 | −0.18, 0.02 | 0.136 | −0.11 | 0.90 | −0.23, −0.003 | 0.045 |
| Stratified by remoteness: | ||||||||
| Non-remote (n = 915) | −0.07 | 0.93 | −0.17, 0.03 | 0.160 | −0.08 | 0.92 | −0.20, 0.03 | 0.150 |
| Remote (n = 1068) | −0.11 | 0.90 | −0.21, −0.01 | 0.033 | −0.12 | 0.89 | −0.22, −0.01 | 0.029 |
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Neo, B.; Nannup, N.; Tilbrook, D.; Michie, C.; Prior, C.; Dunlop, E.; Farrant, B.; Chen, W.S.; Shepherd, C.; Black, L. An Exploratory Study of Serum 25-Hydroxyvitamin D Concentration and Psychological Distress Among Aboriginal and Torres Strait Islander Peoples in Australia. Nutrients 2026, 18, 1563. https://doi.org/10.3390/nu18101563
Neo B, Nannup N, Tilbrook D, Michie C, Prior C, Dunlop E, Farrant B, Chen WS, Shepherd C, Black L. An Exploratory Study of Serum 25-Hydroxyvitamin D Concentration and Psychological Distress Among Aboriginal and Torres Strait Islander Peoples in Australia. Nutrients. 2026; 18(10):1563. https://doi.org/10.3390/nu18101563
Chicago/Turabian StyleNeo, Belinda, Noel Nannup, Dale Tilbrook, Carol Michie, Cindy Prior, Eleanor Dunlop, Brad Farrant, Won Sun Chen, Carrington Shepherd, and Lucinda Black. 2026. "An Exploratory Study of Serum 25-Hydroxyvitamin D Concentration and Psychological Distress Among Aboriginal and Torres Strait Islander Peoples in Australia" Nutrients 18, no. 10: 1563. https://doi.org/10.3390/nu18101563
APA StyleNeo, B., Nannup, N., Tilbrook, D., Michie, C., Prior, C., Dunlop, E., Farrant, B., Chen, W. S., Shepherd, C., & Black, L. (2026). An Exploratory Study of Serum 25-Hydroxyvitamin D Concentration and Psychological Distress Among Aboriginal and Torres Strait Islander Peoples in Australia. Nutrients, 18(10), 1563. https://doi.org/10.3390/nu18101563

