Next Article in Journal
Cross-Sectional Analysis of Sugar-Sweetened Beverage Consumption, Food Security, and Nativity Among Adults: Associations from National Health and Nutrition Examination Survey 2007–2020
Previous Article in Journal
Unlocking Opportunities and Overcoming Challenges in Genetically Engineered Biofortification
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Nutrients
Volume 17
Issue 3
10.3390/nu17030519
nutrients-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Review

Research Progress on the Degradation of Human Milk Oligosaccharides (HMOs) by Bifidobacteria

by
Ruitao Cai
,
Jie Zhang
,
Yingte Song
,
Xiaoyong Liu
* and
Huilian Xu
*
School of Biological Science and Technology, University of Jinan, Jinan 250024, China
*
Authors to whom correspondence should be addressed.
Nutrients 2025, 17(3), 519; https://doi.org/10.3390/nu17030519
Submission received: 3 January 2025 / Revised: 26 January 2025 / Accepted: 28 January 2025 / Published: 30 January 2025
(This article belongs to the Section Prebiotics, Probiotics and Postbiotics)
Browse Figures
Review Reports Versions Notes

Abstract

The purpose of this study was to investigate the degradation mechanism of Bifidobacterium on breast milk oligosaccharides (HMOs) and its application in infant nutrition. The composition and characteristics of HMOs were introduced, and the degradation mechanism of HMOs by Bifidobacterium was described, including intracellular and extracellular digestion and species-specific differences. The interaction between Bifidobacterium and Bacteroides in the process of degrading HMOs and its effect on intestinal microecology were analyzed. The effects of HMO formula milk powder on the intestinal microbiota of infants were discussed, including simulating breast milk composition, regulating intestinal flora and immune function, infection prevention, and brain development. Finally, the research results are summarized, and future research directions are proposed to provide directions for research in the field of infant nutrition.
Keywords: Bifidobacteria; HMOs; degradation mechanism; infant nutrition Bifidobacteria; HMOs; degradation mechanism; infant nutrition

Share and Cite

MDPI and ACS Style

Cai, R.; Zhang, J.; Song, Y.; Liu, X.; Xu, H. Research Progress on the Degradation of Human Milk Oligosaccharides (HMOs) by Bifidobacteria. Nutrients 2025, 17, 519. https://doi.org/10.3390/nu17030519

AMA Style

Cai R, Zhang J, Song Y, Liu X, Xu H. Research Progress on the Degradation of Human Milk Oligosaccharides (HMOs) by Bifidobacteria. Nutrients. 2025; 17(3):519. https://doi.org/10.3390/nu17030519

Chicago/Turabian Style

Cai, Ruitao, Jie Zhang, Yingte Song, Xiaoyong Liu, and Huilian Xu. 2025. "Research Progress on the Degradation of Human Milk Oligosaccharides (HMOs) by Bifidobacteria" Nutrients 17, no. 3: 519. https://doi.org/10.3390/nu17030519

APA Style

Cai, R., Zhang, J., Song, Y., Liu, X., & Xu, H. (2025). Research Progress on the Degradation of Human Milk Oligosaccharides (HMOs) by Bifidobacteria. Nutrients, 17(3), 519. https://doi.org/10.3390/nu17030519

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop