Oral Feeding of NICU Infants: A Global Survey of Current Practices and the Potential of Cold Milk Feeding Intervention
Abstract
1. Introduction
- (1)
- Evaluate the prevalence of cold milk feeding as a therapeutic strategy for managing dysphagia in hospitalized infants.
- (2)
- Identify the gestational age at which oral feeding is typically initiated for those born preterm.
- (3)
- Investigate the types of noninvasive respiratory support, such as nCPAP and HFNC, that are permitted during oral feeding in hospitalized infants.
2. Methods
2.1. Study Design
2.2. Participants
2.3. Survey Distribution Procedures
2.4. Survey Content
- The presence and type of oral feeding protocols;
- The timing of oral feeding initiation;
- The use of cold milk for dysphagia;
- The oral feeding practices during noninvasive respiratory support (nCPAP, HFNC).
2.5. Data Analysis
2.6. Ethical Considerations
3. Results
3.1. Feeding Protocols and Clinical Practices
3.2. Timing of Oral Feeding Initiation
3.3. Awareness and Implementation of Cold Milk Feeding
3.4. Oral Feeding While on Respiratory Support
4. Discussion
4.1. Cue-Based Feeding in Preterm Infants
4.2. Cold Milk Feeding in the NICU: Emerging but Unstandardized
4.3. Lack of Consensus on Feeding During Noninvasive Respiratory Support
4.4. Strengths and Limitations
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
Abbreviations
NICU | Neonatal intensive care unit |
nCPAP | Nasal continuous positive airway pressure |
HFNC | High-flow nasal cannula |
PMA | Postmenstrual age |
SoNPM | Section on Neonatal-Perinatal Medicine |
NYU | New York University |
ASHA | American Speech-Language-Hearing Association |
NANT | National Association of Neonatal Therapists |
SENTAC | Society for Ear Nose and Throat Advancement in Children |
AOTA | American Occupational Therapy Association |
SLP | Speech–language pathologist |
PT | Physical therapist |
OT | Occupational therapist |
PIBBS | Preterm Infant Breastfeeding Behavior Scale |
SOFFI | Supporting Oral Feeding in Fragile Infants |
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Characteristics | N (%) |
---|---|
Role of responders (n= 210) | |
Neonatal Attending | 98 (47%) |
Neonatal Fellow/Advanced Practice Provider | 95 (45%) |
Neonatal Therapist (SLP, OT, PT) | 16 (8%) |
No Response | 1 (0.5%) |
NICU level responses (n = 210) | |
Level II | 11 (5%) |
Level III | 88 (42%) |
Level IV | 108 (52%) |
No Response | 3 (1%) |
Location of the practicing NICU (n = 210) | |
United States | 153 (73%) |
International | 32 (15%) |
No Response | 25 (12%) |
Does your institution currently have an oral feeding protocol for preterm infants? (n = 210) | |
Yes | 152 (72%) |
No | 58 (28%) |
If yes, what protocol do you follow (i.e., IDFS, cue-based feeding, etc.)? (n = 152) | |
IDF | 64 (43%) |
Cue based | 67 (44%) |
Mixed | 12 (8%) |
No response | 7 (5%) |
What corrected gestational age do preterm infants begin oral feeding? (check all that apply) (n = 210) | |
≤33 weeks’ gestation | 76 (36%) |
34 weeks’ gestation | 90 (43%) |
35 weeks’ gestation | 18 (9%) |
Via cues of feeding readiness | 148 (70%) |
IDFS: Infant-Driven Feeding Scale |
Cold Milk Feeding | N (%) |
---|---|
Are you aware of the practice of using cold milk for oral feedings? (n = 210) | |
Yes | 64 (30%) |
No | 144 (69%) |
No response | 2 (1%) |
If yes, does your institution allow cold milk feeding for infants with dysphagia? (n = 64) | |
Yes | 32 (50%) |
No | 31 (48%) |
No response | 1 (2%) |
If yes, at what corrected gestational age would you consider cold milk feeding? (n = 32) | |
>32 weeks’ gestation | 2 (6%) |
>33 weeks’ gestation | 0 (0%) |
>34 weeks’ gestation | 5 (16%) |
>35 weeks’ gestation | 25 (78%) |
If yes to allowing cold milk feeding, how long have you been practicing cold milk? (n = 32) | |
<1 year | 5 (16%) |
1–2 years | 6 (19%) |
3 years | 6 (19%) |
4 years | 1 (3%) |
≥5 years | 13 (40%) |
No response | 1 (3%) |
If yes to allowing cold milk, have you noticed any adverse effects with cold milk feeding? (n = 32) | |
Yes | 8 (25%) |
No | 24 (75%) |
If yes to allowing cold milk, do you combine cold milk modification with thickened feeds? (n = 32) | |
Yes | 9 (28%) |
No | 22 (69%) |
No response | 1 (3%) |
If yes to allowing cold milk, do you discharge the infants to continue cold milk feeding at home? (n = 32) | |
Yes | 14 (44%) |
No | 18 (56%) |
If yes to allowing cold milk, do you have a protocol or guideline for when to initiate cold milk? (n = 32) | |
Yes | 1 (3%) |
No | 31 (97%) |
Cold Milk Feeding Comments | |
---|---|
Comments About Potential Benefits | Comments About Potential Adverse Effects |
“Improves quality of feeds.” “Improved engagement, decreased processing time, timeliness of swallow.” “Improved sensory awareness.” “Improved oral and pharyngeal awareness; decreased signs and symptoms of reflux; improved timing of swallow.” “Because of the better oral sensory input, the swallowing is stronger and more frequent. The flow of the milk is lower, and the baby has more time to swallow.” | “GI discomfort.” “Straining.” “Infant refusal.” “Some infants need temperature modulation, as the cold milk directly from the refrigerator can be too much sensory input, leading to pulling away from the feeding source.” “Intolerance.” “Hypothermia.” |
Oral Feeding on Respiratory Support | N (%) |
---|---|
Does your institution allow preterm infants to orally feed on nCPAP? (n = 210) | |
Yes | 26 (12.4%) |
No | 183 (87.1%) |
No Response | 1 (0.5%) |
If yes, what level of nCPAP? (check all that apply) (n = 26) | |
nCPAP +3 | 11 (42%) |
nCPAP +4 | 10 (38%) |
nCPAP +5 | 16 (62%) |
nCPAP ≥ +6 | 7 (27%) |
Does your institution allow preterm infants to orally feed on HFNC? (n = 210) | |
Yes | 164 (78%) |
No | 44 (21%) |
No response | 2 (1%) |
If yes, at what flow rate can oral feeding occur? (check all that apply) (n = 164) | |
≤2 L | 143 (87%) |
3 L | 55 (34%) |
4 L | 30 (18%) |
>4 L | 15 (9%) |
Feeding on Respiratory Support Comments | |
---|---|
Concerns About Feeding on nCPAP | Concerns About Feeding on HFNC |
“Fear of aspiration.” “Aspiration, choking, and desaturation during oral feeding.” “If they are on CPAP, lung disease is severe enough to pose an aspiration risk.” | “Aspiration.” “Lack of evidence base to support that this is safe/positive.” “Need to use 2 litter/min or less.” “If they are on high flow, then lung disease is severe enough to pose an aspiration risk.” “Too high of a flow causing poor coordination.” |
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Htun, Z.T.; Ferrara-Gonzalez, L.; Kamity, R.; Hanna, N. Oral Feeding of NICU Infants: A Global Survey of Current Practices and the Potential of Cold Milk Feeding Intervention. Nutrients 2025, 17, 2289. https://doi.org/10.3390/nu17142289
Htun ZT, Ferrara-Gonzalez L, Kamity R, Hanna N. Oral Feeding of NICU Infants: A Global Survey of Current Practices and the Potential of Cold Milk Feeding Intervention. Nutrients. 2025; 17(14):2289. https://doi.org/10.3390/nu17142289
Chicago/Turabian StyleHtun, Zeyar T., Louisa Ferrara-Gonzalez, Ranjith Kamity, and Nazeeh Hanna. 2025. "Oral Feeding of NICU Infants: A Global Survey of Current Practices and the Potential of Cold Milk Feeding Intervention" Nutrients 17, no. 14: 2289. https://doi.org/10.3390/nu17142289
APA StyleHtun, Z. T., Ferrara-Gonzalez, L., Kamity, R., & Hanna, N. (2025). Oral Feeding of NICU Infants: A Global Survey of Current Practices and the Potential of Cold Milk Feeding Intervention. Nutrients, 17(14), 2289. https://doi.org/10.3390/nu17142289