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Sarcopenia Prevalence and Risk Factors among Residents in Aged Care
 
 
Article

Prevalence of Sarcopenia in Women with Breast Cancer

1
Internal Medicine and Clinical Nutrition Unit, Department of Clinical Medicine and Surgery, Federico II University Hospital, 80131 Naples, Italy
2
Oncology Unit, Department of Clinical Medicine and Surgery, Federico II University Hospital, 80131 Naples, Italy
*
Author to whom correspondence should be addressed.
Nutrients 2022, 14(9), 1839; https://doi.org/10.3390/nu14091839
Received: 28 March 2022 / Revised: 22 April 2022 / Accepted: 26 April 2022 / Published: 28 April 2022
(This article belongs to the Section Clinical Nutrition)
Sarcopenia is a common finding in patients with cancer and potentially influences the patient’s outcome. The aim of this study was to evaluate the prevalence of sarcopenia, according to the European Working Group on Sarcopenia in Older People, in a sample of women with breast cancer (BC) and a BMI lower than 30 kg/m2. This cross-sectional study was conducted in patients with BC, stage 0-III, and receiving therapy for BC; the women were recruited at the Department of Clinical Medicine and Surgery, Federico II University, Naples, Italy. A control group with similar age and BMI was selected from the internal database. Anthropometry, bioimpedance analysis (BIA) and hand grip strength (HGS) were measured to detect sarcopenia. A total of 122 patients (mean age 49.3 ± 11.0 years, BMI 24.6 ± 3.0 kg/m2) and 80 healthy controls were analyzed. Sarcopenia was found in 13.9% patients with BC, while none of the subjects in the control group was sarcopenic. By comparing BC patients with and without sarcopenia and the control group, the fat-free mass of sarcopenic BC patients were significantly lower than those of both non-sarcopenic BC patients and the control (p < 0.05). The phase angle was also significantly lower in sarcopenic patients (−0.5 degrees, p = 0.048) than in the control group. Considering the prevalence of sarcopenia in patients with BC, our findings suggest the usefulness of body composition and HGS evaluation for early screening of sarcopenia to reduce the risk of associated complications. View Full-Text
Keywords: breast cancer; sarcopenia; body composition; bioimpedance analysis (BIA); hand grip strength (HGS); phase angle (PhA) breast cancer; sarcopenia; body composition; bioimpedance analysis (BIA); hand grip strength (HGS); phase angle (PhA)
MDPI and ACS Style

Morlino, D.; Marra, M.; Cioffi, I.; Santarpia, L.; De Placido, P.; Giuliano, M.; De Angelis, C.; Carrano, S.; Verrazzo, A.; Buono, G.; Naccarato, M.; Di Vincenzo, O.; Speranza, E.; De Placido, S.; Arpino, G.; Pasanisi, F. Prevalence of Sarcopenia in Women with Breast Cancer. Nutrients 2022, 14, 1839. https://doi.org/10.3390/nu14091839

AMA Style

Morlino D, Marra M, Cioffi I, Santarpia L, De Placido P, Giuliano M, De Angelis C, Carrano S, Verrazzo A, Buono G, Naccarato M, Di Vincenzo O, Speranza E, De Placido S, Arpino G, Pasanisi F. Prevalence of Sarcopenia in Women with Breast Cancer. Nutrients. 2022; 14(9):1839. https://doi.org/10.3390/nu14091839

Chicago/Turabian Style

Morlino, Delia, Maurizio Marra, Iolanda Cioffi, Lidia Santarpia, Pietro De Placido, Mario Giuliano, Carmine De Angelis, Simone Carrano, Annarita Verrazzo, Giuseppe Buono, Marianna Naccarato, Olivia Di Vincenzo, Enza Speranza, Sabino De Placido, Grazia Arpino, and Fabrizio Pasanisi. 2022. "Prevalence of Sarcopenia in Women with Breast Cancer" Nutrients 14, no. 9: 1839. https://doi.org/10.3390/nu14091839

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