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Feasibility and Acceptability of a Dietary Intervention to Reduce Salt Intake and Increase High-Nitrate Vegetable Consumption in Malaysian Middle-Aged and Older Adults with Elevated Blood Pressure: Findings from the DePEC-Nutrition Trial

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Global Public Health, Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway 47500, Malaysia
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School of Biomedical, Nutritional and Sports Sciences, Newcastle University, Newcastle upon Tyne NE2 4HH, UK
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South East Asia Community Observatory (SEACO), Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway 45700, Malaysia
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Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway 47500, Malaysia
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Institute of Medical Science Technology, Universiti Kuala Lumpur, Kajang 43000, Malaysia
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District Health Office, Pejabat Kesihatan Daerah (PKD) Segamat, Segamat 85000, Malaysia
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Institute of Mental Health, School of Medicine, University of Nottingham, Nottingham NG7 2TU, UK
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International Institute for Global Health, United Nations University, Kuala Lumpur 56000, Malaysia
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International Centre for Diarrhoeal Disease Research, ICDDR, B, Dhaka 1212, Bangladesh
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Population Health Science Institute, Newcastle University, Newcastle upon Tyne NE4 5PL, UK
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School of Life Sciences, University of Nottingham Medical School, Nottingham NG7 2UH, UK
*
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
These authors contributed equally to this work.
Academic Editor: Gary D. Miller
Nutrients 2022, 14(3), 430; https://doi.org/10.3390/nu14030430
Received: 30 October 2021 / Revised: 8 January 2022 / Accepted: 10 January 2022 / Published: 19 January 2022
(This article belongs to the Section Geriatric Nutrition)
The DePEC-Nutrition trial is a complex dietary and behavioural intervention of salt intake reduction combined with increased high-nitrate vegetable consumption among Malaysian middle-aged and older adults with elevated blood pressure. This study aimed to assess the feasibility and acceptability of the trial. Participants were recruited from the South East Asia Community Observatory (SEACO) database and randomised into one of four groups: (1) low salt; (2) high-nitrate vegetable; (3) combined high-nitrate vegetable and low salt; and (4) control. The intervention included a combination of group counselling sessions, information booklets, reinforcement videos and text messages to modify dietary behaviour. The primary outcomes evaluated were the measures of feasibility and acceptability of (1) recruitment, follow-up attendance and retention; (2) data collection procedures and clinical outcome measures; and (3) individual and combined multi-modal dietary interventions. A total of 74 participants were recruited, and the 10-month retention rate was 73%. Data collection procedures were acceptable with minimal missing data. All intervention strategies were feasible and acceptable, with group counselling being the most acceptable strategy. This study provides important insights into improving the screening process of participants, facilitating their access to the research facilities and refining the measurement protocols and dietary recommendations, which are instrumental in formulating the design of a full-scale definitive DePEC-Nutrition trial. View Full-Text
Keywords: dementia; feasibility trial; randomised controlled trial; dietary nitrate; reduced salt dementia; feasibility trial; randomised controlled trial; dietary nitrate; reduced salt
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MDPI and ACS Style

Lee, S.S.; McGrattan, A.; Soh, Y.C.; Alawad, M.; Su, T.T.; Palanisamy, U.D.; Hussin, A.M.; Kassim, Z.b.; Mohd Ghazali, A.N.b.; Christa Maree Stephan, B.; Allotey, P.; Reidpath, D.D.; Robinson, L.; Mohan, D.; Siervo, M. Feasibility and Acceptability of a Dietary Intervention to Reduce Salt Intake and Increase High-Nitrate Vegetable Consumption in Malaysian Middle-Aged and Older Adults with Elevated Blood Pressure: Findings from the DePEC-Nutrition Trial. Nutrients 2022, 14, 430. https://doi.org/10.3390/nu14030430

AMA Style

Lee SS, McGrattan A, Soh YC, Alawad M, Su TT, Palanisamy UD, Hussin AM, Kassim Zb, Mohd Ghazali ANb, Christa Maree Stephan B, Allotey P, Reidpath DD, Robinson L, Mohan D, Siervo M. Feasibility and Acceptability of a Dietary Intervention to Reduce Salt Intake and Increase High-Nitrate Vegetable Consumption in Malaysian Middle-Aged and Older Adults with Elevated Blood Pressure: Findings from the DePEC-Nutrition Trial. Nutrients. 2022; 14(3):430. https://doi.org/10.3390/nu14030430

Chicago/Turabian Style

Lee, Siew S., Andrea McGrattan, Yee C. Soh, Mawada Alawad, Tin T. Su, Uma D. Palanisamy, Azizah M. Hussin, Zaid b. Kassim, Ahmad N.b. Mohd Ghazali, Blossom Christa Maree Stephan, Pascale Allotey, Daniel D. Reidpath, Louise Robinson, Devi Mohan, and Mario Siervo. 2022. "Feasibility and Acceptability of a Dietary Intervention to Reduce Salt Intake and Increase High-Nitrate Vegetable Consumption in Malaysian Middle-Aged and Older Adults with Elevated Blood Pressure: Findings from the DePEC-Nutrition Trial" Nutrients 14, no. 3: 430. https://doi.org/10.3390/nu14030430

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