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Article

Chemical Characterization and In Vivo Toxicological Safety Evaluation of Emu Oil

1
Sericultural & Agri-Food Research Institute, Guangdong Academy of Agricultural Sciences Key Laboratory of Functional Foods, Ministry of Agriculture and Rural Affairs, Guangdong Key Laboratory of Agricultural Products Processing, Guangzhou 510610, China
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College of Food Science and Engineering, Guangdong Province Key Laboratory for Green Processing of Natural Products and Product Safety, Engineering Research Center of Starch and Plant Protein Deep Processing, Ministry of Education, South China University of Technology, Guangzhou 510640, China
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School of Chemical Engineering and Energy Technology, Dongguan University of Technology, Dongguan 523808, China
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Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, Key Laboratory for Chemical Biology of Fujian Province, Xia-men University, Xiamen 361000, China
*
Authors to whom correspondence should be addressed.
Academic Editor: Licia Iacoviello
Nutrients 2022, 14(11), 2238; https://doi.org/10.3390/nu14112238
Received: 8 March 2022 / Revised: 24 May 2022 / Accepted: 25 May 2022 / Published: 27 May 2022
(This article belongs to the Special Issue Function and Nutritional Value of Oils)
In this study, the physicochemical properties, fatty acid composition, antioxidant activities, and in vitro as well as in vivo toxicological safety of emu oil were investigated. Emu oil was shown to have a low acid and peroxide value, low amounts of carotenoid and phenolic compounds, and high doses of oleic acid and linoleic acid. Furthermore, in a bacterial reverse mutation assay, emu oil demonstrated no change in the amount of revertant colonies for all strains. In a chromosomal assay, no aberrations occurred in any of the emu oil treatment groups (1.25, 2.5, and 5 μg/mL). In the bone marrow micronucleus test, emu oil up to 20 mL/kg showed no significant increase in the incidence of micronucleated polychromatic erythrocytes. Moreover, emu oil up to 19.3 mg/kg body weight did not affect body weight in an acute oral toxicity study. These results are crucial for the adoption of emu oil as an alternative source of edible oil. View Full-Text
Keywords: emu oil; fatty acid; antioxidant activities; toxicological safety emu oil; fatty acid; antioxidant activities; toxicological safety
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MDPI and ACS Style

Lan, M.; Li, L.; Luo, S.; Chen, J.; Yi, X.; Zhang, X.; Li, B.; Chen, Z. Chemical Characterization and In Vivo Toxicological Safety Evaluation of Emu Oil. Nutrients 2022, 14, 2238. https://doi.org/10.3390/nu14112238

AMA Style

Lan M, Li L, Luo S, Chen J, Yi X, Zhang X, Li B, Chen Z. Chemical Characterization and In Vivo Toxicological Safety Evaluation of Emu Oil. Nutrients. 2022; 14(11):2238. https://doi.org/10.3390/nu14112238

Chicago/Turabian Style

Lan, Meijuan, Lin Li, Shengkai Luo, Juncheng Chen, Xiaofeng Yi, Xia Zhang, Bing Li, and Zhiyi Chen. 2022. "Chemical Characterization and In Vivo Toxicological Safety Evaluation of Emu Oil" Nutrients 14, no. 11: 2238. https://doi.org/10.3390/nu14112238

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