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Nutrients
Volume 14
Issue 1
10.3390/nu14010191
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Review

The Role of the Gut Microbiota on the Beneficial Effects of Ketogenic Diets

by
Ilias Attaye
*,
Sophie van Oppenraaij
,
Moritz V. Warmbrunn
and
Max Nieuwdorp
*
Department of Internal Medicine and Vascular Medicine, Amsterdam University Medical Center, Location Academic Medical Center, 1105 Amsterdam, The Netherlands
*
Authors to whom correspondence should be addressed.
Nutrients 2022, 14(1), 191; https://doi.org/10.3390/nu14010191
Submission received: 8 November 2021 / Revised: 27 December 2021 / Accepted: 28 December 2021 / Published: 31 December 2021
(This article belongs to the Special Issue Ketogenic Diet and Metabolism)
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Abstract

The ketogenic diet is a dietary regime focused on strongly reducing carbohydrate intake and increasing fat intake; leading to a state of ketosis. The ketogenic diet has gained much popularity over the years due to its effects on promoting weight loss, increasing insulin sensitivity and reducing dyslipidaemia. All these factors play a crucial role in the development of cardio-metabolic diseases; one of the greatest health challenges of the time. Moreover, the ketogenic diet has been known to reduce (epileptic) seizure activity. It is still poorly understood how following a ketogenic diet can lead to these beneficial metabolic effects. However, in recent years it has become clear that diet and the gut microbiota interact with one another and thus influence host health. The goal of this review is to summarize the current state of knowledge regarding the beneficial metabolic effects of the ketogenic diet and the role of gut microbiota in these effects.
Keywords: diet; ketogenic diet; gut microbiota; seizure; cardiometabolic disease diet; ketogenic diet; gut microbiota; seizure; cardiometabolic disease

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MDPI and ACS Style

Attaye, I.; van Oppenraaij, S.; Warmbrunn, M.V.; Nieuwdorp, M. The Role of the Gut Microbiota on the Beneficial Effects of Ketogenic Diets. Nutrients 2022, 14, 191. https://doi.org/10.3390/nu14010191

AMA Style

Attaye I, van Oppenraaij S, Warmbrunn MV, Nieuwdorp M. The Role of the Gut Microbiota on the Beneficial Effects of Ketogenic Diets. Nutrients. 2022; 14(1):191. https://doi.org/10.3390/nu14010191

Chicago/Turabian Style

Attaye, Ilias, Sophie van Oppenraaij, Moritz V. Warmbrunn, and Max Nieuwdorp. 2022. "The Role of the Gut Microbiota on the Beneficial Effects of Ketogenic Diets" Nutrients 14, no. 1: 191. https://doi.org/10.3390/nu14010191

APA Style

Attaye, I., van Oppenraaij, S., Warmbrunn, M. V., & Nieuwdorp, M. (2022). The Role of the Gut Microbiota on the Beneficial Effects of Ketogenic Diets. Nutrients, 14(1), 191. https://doi.org/10.3390/nu14010191

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